Confocal immunofluorescence image of the cytoplasmic membrane E-cadherin (green) (A), nuclear ZEB2 (red) (B) and nuclear staining with Hoechst (blue) (C). Note that most of the neoplastic cells present both, positivity for ZEB2 and negativity for E-cadherin. Some neoplastic cells reveal concomitantly positivity for ZEB2 and weak intensity E-cadherin expression. Nuclear localization of ZEB2 was confirmed for the merged image (D) that demonstrates the co-localisation of ZEB2 with Hoechst. Images are representative of what was observed in 10 fields of an IMPC case. Scale Bar = 20 μm.</p
In progression of tumours, resulting from, i.e., release of cells from the parental tumour and devel...
<p>(A, B) Shows a heterogeneous population of cellular expression in both (A) MARY-X primary tumors ...
<p>Representative images ErbB2, Twist2 and E-cadherin IHC staining in tumor central areas (TC, first...
Number of neoplastic epithelial cells stained for E-cadherin (ECAD) and ZEB2 concomitantly (ECAD+ZEB...
Number of neoplastic epithelial cells stained for E-cadherin (ECAD) and ZEB2 in immunofluorescence a...
The E-cadherin loss has frequently been associated with transcriptional repression mediated by trans...
Immunohistochemical (IHC) and RNA In Situ Hybridization (ISH) staining for ZEB2 and E-cadherin (CDH1...
(A) Invasive micropapillary area of a IMPC classified as 4+ for E-cadherin. The case reveals >10 dot...
none5The reduction or loss of E-cadherin, a calcium-dependent epithelial cell adhesion molecule, has...
<p>(A) High ZEB2 expression was observed in an RCC (case 87), in which more than 90% of the tumor ce...
The objective of the present investigation was to study the expression of c-erbB-2 and MIB-1 and try...
Fifty-four canine mammary lesions (15 hyperplasias, 7 adenomas and 32 carcinomas) were submitted to ...
<p>DAPI (blue) and E29 (red) staining are used to mark nucleus and epithelial cells of normal (<b>A<...
Mast cell tumors (MCTs) are the most frequent round cell tumors in dogs and comprise approximately 2...
Canine mammary tumors (CMTs) have histopathological, epidemiologic and clinical characteristics simi...
In progression of tumours, resulting from, i.e., release of cells from the parental tumour and devel...
<p>(A, B) Shows a heterogeneous population of cellular expression in both (A) MARY-X primary tumors ...
<p>Representative images ErbB2, Twist2 and E-cadherin IHC staining in tumor central areas (TC, first...
Number of neoplastic epithelial cells stained for E-cadherin (ECAD) and ZEB2 concomitantly (ECAD+ZEB...
Number of neoplastic epithelial cells stained for E-cadherin (ECAD) and ZEB2 in immunofluorescence a...
The E-cadherin loss has frequently been associated with transcriptional repression mediated by trans...
Immunohistochemical (IHC) and RNA In Situ Hybridization (ISH) staining for ZEB2 and E-cadherin (CDH1...
(A) Invasive micropapillary area of a IMPC classified as 4+ for E-cadherin. The case reveals >10 dot...
none5The reduction or loss of E-cadherin, a calcium-dependent epithelial cell adhesion molecule, has...
<p>(A) High ZEB2 expression was observed in an RCC (case 87), in which more than 90% of the tumor ce...
The objective of the present investigation was to study the expression of c-erbB-2 and MIB-1 and try...
Fifty-four canine mammary lesions (15 hyperplasias, 7 adenomas and 32 carcinomas) were submitted to ...
<p>DAPI (blue) and E29 (red) staining are used to mark nucleus and epithelial cells of normal (<b>A<...
Mast cell tumors (MCTs) are the most frequent round cell tumors in dogs and comprise approximately 2...
Canine mammary tumors (CMTs) have histopathological, epidemiologic and clinical characteristics simi...
In progression of tumours, resulting from, i.e., release of cells from the parental tumour and devel...
<p>(A, B) Shows a heterogeneous population of cellular expression in both (A) MARY-X primary tumors ...
<p>Representative images ErbB2, Twist2 and E-cadherin IHC staining in tumor central areas (TC, first...