The Oxygen Minimum Zone (OMZ) of the Tropical South Eastern Pacific (TSEP) is one of the most intensely deoxygenated water masses of the global ocean. It is strongly affected at interannual time scales by El Niño (EN) and La Niña (LN) due to its proximity to the equatorial Pacific. In this work, the physical and biogeochemical processes associated with the subsurface oxygen variability during EN and LN in the period 1958–2008 were studied using a regional coupled physical-biogeochemical model and in situ observations. The passage of intense remotely forced coastal trapped waves caused a strong deepening (shoaling) of the OMZ upper limit during EN (LN). A close correlation between the OMZ upper limit and thermocline depths was found close to...