SPC-01 graft. Transplanted cells were stained with human marker Ku80 to visualize the graft within spinal cord tissue. SPC-01 cells are indicated with white arrows (A). Grafts of SPC-01 cells formed dense clusters outlined in black, which were clearly distinguishable in both cresyl violet staining (B) and NFkB (p65) DAB staining (C). (PDF 755 kb
Figure S4. Summary of flow cytometry gating strategy used for phenotypical analysis of helper T cell...
Showing locomotor coordination evaluated by the rotarod test. The time spent on the rod gradually in...
Table S1. Secretome analysis of hES-AS, differentiated for 7Â days or 28Â days. The 220 most secrete...
Figure S1. MSCs pre- and post transplantation. Figure S1A, B mCherry+MSCs prior to transplantation (...
Representative tissue sections of the spinal cord (upper row, 12 weeks after transplant) and brain (...
Figure S2. Physical parameters and gating strategy of transplanted MSCs. Figure S2A-C non-transplant...
Additional file 1. Supplementary Figure S1, Figure S2, Figure S3, Figure S4, and Table S1
Figure S1. hES-AS produce and secrete neurotrophic factors. Conditioned media of 24Â h from cultures...
Figure S5. Interaction between transplanted MSCs and immune cells. MSCs in relation to immune cells ...
Efficient BrdU labeling and in vitro detection of sorted neural progenitors. A Representative bright...
Spinally grafted CoMo-NSCs-derived neurons show a long-term engraftment, no tumor formation and exte...
Figure S4. Proliferation and expression of CD29, Sca1 and CD45 in non-transplanted MSCs. Figure S4A ...
Spinally grafted clonal NSCs give rise to mature astrocyte and oligodendrocytes in the immunodeficie...
Figure S1. Characterization of GFP-BMSCs in vitro. (A, B, C) Representative images of CD44 biomarker...
Figure S6. Caspase-3 positive control. Mouse liver tissue stained with Caspase-3 acting as positive ...
Figure S4. Summary of flow cytometry gating strategy used for phenotypical analysis of helper T cell...
Showing locomotor coordination evaluated by the rotarod test. The time spent on the rod gradually in...
Table S1. Secretome analysis of hES-AS, differentiated for 7Â days or 28Â days. The 220 most secrete...
Figure S1. MSCs pre- and post transplantation. Figure S1A, B mCherry+MSCs prior to transplantation (...
Representative tissue sections of the spinal cord (upper row, 12 weeks after transplant) and brain (...
Figure S2. Physical parameters and gating strategy of transplanted MSCs. Figure S2A-C non-transplant...
Additional file 1. Supplementary Figure S1, Figure S2, Figure S3, Figure S4, and Table S1
Figure S1. hES-AS produce and secrete neurotrophic factors. Conditioned media of 24Â h from cultures...
Figure S5. Interaction between transplanted MSCs and immune cells. MSCs in relation to immune cells ...
Efficient BrdU labeling and in vitro detection of sorted neural progenitors. A Representative bright...
Spinally grafted CoMo-NSCs-derived neurons show a long-term engraftment, no tumor formation and exte...
Figure S4. Proliferation and expression of CD29, Sca1 and CD45 in non-transplanted MSCs. Figure S4A ...
Spinally grafted clonal NSCs give rise to mature astrocyte and oligodendrocytes in the immunodeficie...
Figure S1. Characterization of GFP-BMSCs in vitro. (A, B, C) Representative images of CD44 biomarker...
Figure S6. Caspase-3 positive control. Mouse liver tissue stained with Caspase-3 acting as positive ...
Figure S4. Summary of flow cytometry gating strategy used for phenotypical analysis of helper T cell...
Showing locomotor coordination evaluated by the rotarod test. The time spent on the rod gradually in...
Table S1. Secretome analysis of hES-AS, differentiated for 7Â days or 28Â days. The 220 most secrete...