Additional file 6: of Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients

Figure S1. Gene expression of BACH2 and effector memory-related genes: PRDM1, IL-4 and IFNγ in CD4+ T-cells from healthy donors. (A) BACH2 mRNA expression decreased with age in CD4+ (r = − 0.67, p < 0.0001) (B) PRDM1 mRNA expression increased with age in CD4+ (r = − 0.61, p = 0.0001), (C) IL-4 mRNA expression increased with age in CD4+ (r = − 0.66, p < 0.0001), (D) IFNγ mRNA expression showed non-significant change with age in CD4+ (r = − 0.28, p = 0.0641). Significant p values (< 0.05) and Spearman r values are shown. (TIF 6567 kb