JIMT-1 and MDA-MB-453 cell lines display relative resistance to lapatinib.
- Loral E. Showalter (4170238)
- Crystal Oechsle (6243821)
- Nirmala Ghimirey (6243824)
- Chase Steele (6243827)
- Brian J. Czerniecki (285700)
- Gary K. Koski (285702)
Publication date
January 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
Cultured SK-BR-3, JIMT-1, HCC1419, and MDA-MB-453 cells were treated with increasing concentrations of lapatinib (0–4μM). After 72 hours incubation, resazurin sodium salt (Alamar Blue dye) was added to each well and further incubated until color change was noted, and optical densities of supernatants read spectrophotometrically at 630nM. Shown are composite data from at least three trials per cell line expressed as mean optical density +/- SEM.</p
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