Additional file 2: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Additional file 8: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Geraldine Vijay (6437930)
Na Zhao (112953)
Petra Hollander (6437933)
Mike Toneff (6437936)
Robiya Joseph (6437939)
Mika Pietila (6437942)
Joseph Taube (4458358)
Tapasree Sarkar (6437945)
Esmeralda Ramirez-Pena (6437948)
Steven Werden (6437951)
Maryam Shariati (4043501)
Ruli Gao (6437954)
Mary Sobieski (5690516)
Clifford Stephan (6437957)
Nathalie Sphyris (6437960)
Noayuki Miura (6437963)
Peter Davies (95719)
Jeffrey Chang (3945326)
Rama Soundararajan (6437966)
Jeffrey Rosen (3172593)
Sendurai Mani (4043519)

March 2019

Figure S6. KmPlots were generated for several major players of the Wnt signaling pathway using the K...

Additional file 1: of Nck-associated protein 1 associates with HSP90 to drive metastasis in human non-small-cell lung cancer

Yuanping Xiong (491614)
Leilei He (3093528)
Chloe Shay (4104376)
Liwei Lang (577095)
Jenni Loveless (6457445)
Jieqing Yu (6457448)
Ron Chemmalakuzhy (5431388)
Hongqun Jiang (6457451)
Manran Liu (95074)
Yong Teng (205028)

March 2019

Figure S1. 17-AAG exhibits a superior effect on suppression of NAP1 proteins compared with other two...

Additional file 3: of Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38

Katharina Gohr (4571839)
Alexandra Hamacher (534446)
Laura Engelke (1867372)
Matthias Kassack (2160217)

November 2017

MTT assay of combination of RTK inhibitors with cisplatin. Influence of 48 h preincubation with 1.5 ...

Additional file 1: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Nuramalina Mumin (6262541)
Neele Drobnitzky (6262547)
Agata Patel (6262553)
Luiza Lourenco (6262556)
Fiona Cahill (6262562)
Yanyan Jiang (253354)
Anthony Kong (94738)
Anderson Ryan (482874)

January 2019

Table S1. The top 20 most significantly enriched pathways seen in HSP90i-resistant clones. Pathway e...

Additional file 3: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Nuramalina Mumin (6262541)
Neele Drobnitzky (6262547)
Agata Patel (6262553)
Luiza Lourenco (6262556)
Fiona Cahill (6262562)
Yanyan Jiang (253354)
Anthony Kong (94738)
Anderson Ryan (482874)

January 2019

Table S2. Compounds that were selectively cytotoxic to parental Hs578T cells compared with HSP90i-re...

Additional file 4: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Nuramalina Mumin (6262541)
Neele Drobnitzky (6262547)
Agata Patel (6262553)
Luiza Lourenco (6262556)
Fiona Cahill (6262562)
Yanyan Jiang (253354)
Anthony Kong (94738)
Anderson Ryan (482874)

January 2019

Table S3. Compounds that were differentially cytotoxic to HSP90i-resistant clone CR3 in the presence...

Additional file 2: of Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer

Murugan Kalimutho (6375365)
Debottam Sinha (6375368)
Deepak Mittal (4967743)
Sriganesh Srihari (3542939)
Devathri Nanayakkara (6375371)
Shagufta Shafique (759049)
Prahlad Raninga (6375374)
Purba Nag (6375377)
Kate Parsons (6375380)
Kum Khanna (3588107)

February 2019

Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...

Additional file 1: of Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

Maki Tanioka (411765)
Kevin Mott (6031694)
Daniel Hollern (6031697)
Cheng Fan (17164)
David Darr (218674)
Charles Perou (3530138)

November 2018

Figure S1. Long-term survival results for eight mouse models of basal breast cancer. Figure S2. Anal...

Additional file 3: of Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer

Murugan Kalimutho (6375365)
Debottam Sinha (6375368)
Deepak Mittal (4967743)
Sriganesh Srihari (3542939)
Devathri Nanayakkara (6375371)
Shagufta Shafique (759049)
Prahlad Raninga (6375374)
Purba Nag (6375377)
Kate Parsons (6375380)
Kum Khanna (3588107)

February 2019

Figure S2: (A) Hs578T cells were exposed to different concentrations of MEK1/2 inhibitor (AZD6244) a...

Additional file 2: of Development of a test that measures real-time HER2 signaling function in live breast cancer cell lines and primary cells

Yao Huang (216100)
David Burns (3843406)
Benjamin Rich (3843391)
Ian MacNeil (3843403)
Abhijit Dandapat (3179052)
Sajjad Soltani (3843400)
Samantha Myhre (3843397)
Brian Sullivan (337130)
Carol Lange (562170)
Leo Furcht (3843394)
Lance Laing (3843388)

March 2017

Figure S1. The PI3K/AKT pathway significantly contributes to the ligand-driven HER2 signaling activi...

Additional file 2: Figure S1. of HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

Qiuran Xu (4103755)
Jianfeng Tu (4103758)
Changwei Dou (3554573)
Jun Zhang (48506)
Liu Yang (23752)
Xin Liu (43569)
Kefeng Lei (4708894)
Zhikui Liu (3554570)
Yufeng Wang (274657)
Lijie Li (1438762)
Hangxing Bao (4103752)
Jiahui Wang (746367)
Kangsheng Tu (428934)

December 2017

Knockdown of HSP90 reduced the protein level of PKM2. Hep3B cells were transfected with HSP90 shRNA ...

Additional file 1 of Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells

Seo Yun Moon (11295001)
Heejin Lee (5059841)
Seoree Kim (10338758)
Ji Hyung Hong (5587733)
Sang Hoon Chun (6009698)
Hee Yeon Lee (11295004)
Keunsoo Kang (204695)
Ho Shik Kim (11295007)
Hye Sung Won (10812974)
Yoon Ho Ko (5587736)

August 2021

Additional file 1: Supplementary Figure 1. a. The protein expression levels of STAT5 and p-STAT5 wer...

Additional file 1: of Blockade of PDGFRÎ˛ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltrationÂ in triple-negative breast cancer

Murugan Kalimutho (6375365)
Debottam Sinha (6375368)
Deepak Mittal (4967743)
Sriganesh Srihari (3542939)
Devathri Nanayakkara (6375371)
Shagufta Shafique (759049)
Prahlad Raninga (6375374)
Purba Nag (6375377)
Kate Parsons (6375380)
Kum Khanna (3588107)

February 2019

Table S1. List of small interfering RNA (siRNA), primers for mutagenesis, primers for RT-qPCR and an...

Additional file 2: of Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

Maki Tanioka (411765)
Kevin Mott (6031694)
Daniel Hollern (6031697)
Cheng Fan (17164)
David Darr (218674)
Charles Perou (3530138)

November 2018

Table S1. Genes in mouse and human version of Myc signatures. Table S2. A. Upregulated and downregul...

Additional file 5: Figure S4. of HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

Qiuran Xu (4103755)
Jianfeng Tu (4103758)
Changwei Dou (3554573)
Jun Zhang (48506)
Liu Yang (23752)
Xin Liu (43569)
Kefeng Lei (4708894)
Zhikui Liu (3554570)
Yufeng Wang (274657)
Lijie Li (1438762)
Hangxing Bao (4103752)
Jiahui Wang (746367)
Kangsheng Tu (428934)

December 2017

HSP90 knockdown led to decreased Ser/Thr phosphorylation of PKM2. Hep3B cells were transfected with ...

Additional file 8: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Geraldine Vijay (6437930)
Na Zhao (112953)
Petra Hollander (6437933)
Mike Toneff (6437936)
Robiya Joseph (6437939)
Mika Pietila (6437942)
Joseph Taube (4458358)
Tapasree Sarkar (6437945)
Esmeralda Ramirez-Pena (6437948)
Steven Werden (6437951)
Maryam Shariati (4043501)
Ruli Gao (6437954)
Mary Sobieski (5690516)
Clifford Stephan (6437957)
Nathalie Sphyris (6437960)
Noayuki Miura (6437963)
Peter Davies (95719)
Jeffrey Chang (3945326)
Rama Soundararajan (6437966)
Jeffrey Rosen (3172593)
Sendurai Mani (4043519)

March 2019

Figure S6. KmPlots were generated for several major players of the Wnt signaling pathway using the K...

Additional file 1: of Nck-associated protein 1 associates with HSP90 to drive metastasis in human non-small-cell lung cancer

Yuanping Xiong (491614)
Leilei He (3093528)
Chloe Shay (4104376)
Liwei Lang (577095)
Jenni Loveless (6457445)
Jieqing Yu (6457448)
Ron Chemmalakuzhy (5431388)
Hongqun Jiang (6457451)
Manran Liu (95074)
Yong Teng (205028)

March 2019

Figure S1. 17-AAG exhibits a superior effect on suppression of NAP1 proteins compared with other two...

Additional file 3: of Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38

Katharina Gohr (4571839)
Alexandra Hamacher (534446)
Laura Engelke (1867372)
Matthias Kassack (2160217)

November 2017

MTT assay of combination of RTK inhibitors with cisplatin. Influence of 48 h preincubation with 1.5 ...

Additional file 1: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Nuramalina Mumin (6262541)
Neele Drobnitzky (6262547)
Agata Patel (6262553)
Luiza Lourenco (6262556)
Fiona Cahill (6262562)
Yanyan Jiang (253354)
Anthony Kong (94738)
Anderson Ryan (482874)

January 2019

Table S1. The top 20 most significantly enriched pathways seen in HSP90i-resistant clones. Pathway e...

Additional file 3: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Nuramalina Mumin (6262541)
Neele Drobnitzky (6262547)
Agata Patel (6262553)
Luiza Lourenco (6262556)
Fiona Cahill (6262562)
Yanyan Jiang (253354)
Anthony Kong (94738)
Anderson Ryan (482874)

January 2019

Table S2. Compounds that were selectively cytotoxic to parental Hs578T cells compared with HSP90i-re...

Additional file 4: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Nuramalina Mumin (6262541)
Neele Drobnitzky (6262547)
Agata Patel (6262553)
Luiza Lourenco (6262556)
Fiona Cahill (6262562)
Yanyan Jiang (253354)
Anthony Kong (94738)
Anderson Ryan (482874)

January 2019

Table S3. Compounds that were differentially cytotoxic to HSP90i-resistant clone CR3 in the presence...

Additional file 2: of Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer

Murugan Kalimutho (6375365)
Debottam Sinha (6375368)
Deepak Mittal (4967743)
Sriganesh Srihari (3542939)
Devathri Nanayakkara (6375371)
Shagufta Shafique (759049)
Prahlad Raninga (6375374)
Purba Nag (6375377)
Kate Parsons (6375380)
Kum Khanna (3588107)

February 2019

Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...

Additional file 1: of Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

Maki Tanioka (411765)
Kevin Mott (6031694)
Daniel Hollern (6031697)
Cheng Fan (17164)
David Darr (218674)
Charles Perou (3530138)

November 2018

Figure S1. Long-term survival results for eight mouse models of basal breast cancer. Figure S2. Anal...

Additional file 3: of Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer

Murugan Kalimutho (6375365)
Debottam Sinha (6375368)
Deepak Mittal (4967743)
Sriganesh Srihari (3542939)
Devathri Nanayakkara (6375371)
Shagufta Shafique (759049)
Prahlad Raninga (6375374)
Purba Nag (6375377)
Kate Parsons (6375380)
Kum Khanna (3588107)

February 2019

Figure S2: (A) Hs578T cells were exposed to different concentrations of MEK1/2 inhibitor (AZD6244) a...

Additional file 2: of Development of a test that measures real-time HER2 signaling function in live breast cancer cell lines and primary cells

Yao Huang (216100)
David Burns (3843406)
Benjamin Rich (3843391)
Ian MacNeil (3843403)
Abhijit Dandapat (3179052)
Sajjad Soltani (3843400)
Samantha Myhre (3843397)
Brian Sullivan (337130)
Carol Lange (562170)
Leo Furcht (3843394)
Lance Laing (3843388)

March 2017

Figure S1. The PI3K/AKT pathway significantly contributes to the ligand-driven HER2 signaling activi...

Additional file 2: Figure S1. of HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

Qiuran Xu (4103755)
Jianfeng Tu (4103758)
Changwei Dou (3554573)
Jun Zhang (48506)
Liu Yang (23752)
Xin Liu (43569)
Kefeng Lei (4708894)
Zhikui Liu (3554570)
Yufeng Wang (274657)
Lijie Li (1438762)
Hangxing Bao (4103752)
Jiahui Wang (746367)
Kangsheng Tu (428934)

December 2017

Knockdown of HSP90 reduced the protein level of PKM2. Hep3B cells were transfected with HSP90 shRNA ...

Additional file 1 of Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells

Seo Yun Moon (11295001)
Heejin Lee (5059841)
Seoree Kim (10338758)
Ji Hyung Hong (5587733)
Sang Hoon Chun (6009698)
Hee Yeon Lee (11295004)
Keunsoo Kang (204695)
Ho Shik Kim (11295007)
Hye Sung Won (10812974)
Yoon Ho Ko (5587736)

August 2021

Additional file 1: Supplementary Figure 1. a. The protein expression levels of STAT5 and p-STAT5 wer...

Additional file 1: of Blockade of PDGFRÎ˛ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltrationÂ in triple-negative breast cancer

Murugan Kalimutho (6375365)
Debottam Sinha (6375368)
Deepak Mittal (4967743)
Sriganesh Srihari (3542939)
Devathri Nanayakkara (6375371)
Shagufta Shafique (759049)
Prahlad Raninga (6375374)
Purba Nag (6375377)
Kate Parsons (6375380)
Kum Khanna (3588107)

February 2019

Table S1. List of small interfering RNA (siRNA), primers for mutagenesis, primers for RT-qPCR and an...

Additional file 2: of Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

Maki Tanioka (411765)
Kevin Mott (6031694)
Daniel Hollern (6031697)
Cheng Fan (17164)
David Darr (218674)
Charles Perou (3530138)

November 2018

Table S1. Genes in mouse and human version of Myc signatures. Table S2. A. Upregulated and downregul...

Additional file 5: Figure S4. of HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

Qiuran Xu (4103755)
Jianfeng Tu (4103758)
Changwei Dou (3554573)
Jun Zhang (48506)
Liu Yang (23752)
Xin Liu (43569)
Kefeng Lei (4708894)
Zhikui Liu (3554570)
Yufeng Wang (274657)
Lijie Li (1438762)
Hangxing Bao (4103752)
Jiahui Wang (746367)
Kangsheng Tu (428934)

December 2017

HSP90 knockdown led to decreased Ser/Thr phosphorylation of PKM2. Hep3B cells were transfected with ...

Additional file 8: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

Geraldine Vijay (6437930)
Na Zhao (112953)
Petra Hollander (6437933)
Mike Toneff (6437936)
Robiya Joseph (6437939)
Mika Pietila (6437942)
Joseph Taube (4458358)
Tapasree Sarkar (6437945)
Esmeralda Ramirez-Pena (6437948)
Steven Werden (6437951)
Maryam Shariati (4043501)
Ruli Gao (6437954)
Mary Sobieski (5690516)
Clifford Stephan (6437957)
Nathalie Sphyris (6437960)
Noayuki Miura (6437963)
Peter Davies (95719)
Jeffrey Chang (3945326)
Rama Soundararajan (6437966)
Jeffrey Rosen (3172593)
Sendurai Mani (4043519)

March 2019

Figure S6. KmPlots were generated for several major players of the Wnt signaling pathway using the K...

Additional file 1: of Nck-associated protein 1 associates with HSP90 to drive metastasis in human non-small-cell lung cancer

Yuanping Xiong (491614)
Leilei He (3093528)
Chloe Shay (4104376)
Liwei Lang (577095)
Jenni Loveless (6457445)
Jieqing Yu (6457448)
Ron Chemmalakuzhy (5431388)
Hongqun Jiang (6457451)
Manran Liu (95074)
Yong Teng (205028)

March 2019

Figure S1. 17-AAG exhibits a superior effect on suppression of NAP1 proteins compared with other two...

Additional file 3: of Inhibition of PI3K/Akt/mTOR overcomes cisplatin resistance in the triple negative breast cancer cell line HCC38

Katharina Gohr (4571839)
Alexandra Hamacher (534446)
Laura Engelke (1867372)
Matthias Kassack (2160217)

November 2017

MTT assay of combination of RTK inhibitors with cisplatin. Influence of 48 h preincubation with 1.5 ...

Additional file 2: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Abstract

Extracted data

Additional file 2: of Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer

Abstract

Extracted data

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