Additional file 1: of Spatial patterns of white matter hyperintensities associated with Alzheimer’s disease risk factors in a cognitively healthy middle-aged cohort

Figure S1. Description of global and regional WMH burden. Figure S2. Cross-correlation between CAIDE-I percentage of dementia and its individual risk factors. Figure S3. Regional patterns of WMH associations with hypertension measured by different classifications. Table S1. Risk factors taken into account to derive CAIDE dementia risk scores and their corresponding points assigned. Table S2. Associations between global WMH and individual conditions to assess hypertension. Table S3. Comparison of CAIDE risk factors between hypertensive and nonhypertensive participants. Table S4. Comparison of CAIDE risk factors between nonhypercholesterolemic and hypercholesterolemic participants. Table S5. Comparison of CAIDE risk factors between women and men. Table S6. Comparison of CAIDE risk factors between physically inactive and active participants. Table S7. Comparison of CAIDE risk factors between APOE-ε2 carriers and APOE-ε3 homozygotes. Table S8. Comparison of CAIDE risk factors between participants with maternal family history and no family history of AD. (DOCX 1802 kb