Plasmablast populations and CD21 expression in leprosy immune reactions.

Plasmablast populations were proportionally greater in people with ENL (3A) and fewer of these plasmablasts were CD21+ compared to non-reaction groups (3B). Comparison was made between MB patients that do not develop immune reactions in 2-years of follow-up (Reaction-/-) with those with MB who developed RR (RR-/+) or ENL (ENL -/+) (ANOVA or Kruskal-Wallis test). Those patients who developed reactions during the cohort were also compared with patients with active immune reactions (RR+ and ENL+) (Student’s t test or Mann-Whitney test). * p ≤ 0.05. The horizontal bar is the mean and the vertical bars the standard error of the mean (SEM).