ROC curve characteristics of HbA1c that corresponded with fasting plasma glucose (FPG) ≥5.6 mmol/L (A), FPG ≥5.6mmol/L or 2-hour oral glucose tolerance test (OGTT) ≥7.8mmolL (B), and FPG ≥7.0mmol/L and 2-hour OGTT ≥11.1mmol/L (C) in HIV-infected participants without known diabetes.

The ROC curves show the same optimal cut-point of HbA1c of 5.75% (39.3 mmol/mol) for diagnosing dysglycaemia based on FPG (A) (AUC: 0.733, sensitivity: 54%, specificity: 84%) or based on OGTT (B) (AUC: 0.722, sensitivity: 52%, specificity: 85%), and the optimal HbA1c of 5.85% (40.4 mmol/mol) for screen-detected diabetes (C) (AUC: 0.797, sensitivity: 63%, specificity: 86%).