Near basal plane of the cell layers p53 null cell shows reduced appearance of cryptic lamellipodia.
- Shijie He (3286359)
- Christopher V. Carman (6288464)
- Jung Hyun Lee (704149)
- Bo Lan (4434580)
- Stephan Koehler (1567771)
- Lior Atia (6288467)
- Chan Young Park (264360)
- Jae Hun Kim (384180)
- Jennifer A. Mitchel (204483)
- Jin-Ah Park (3827329)
- James P. Butler (175276)
- Quan Lu (153192)
- Jeffrey J. Fredberg (136202)
Publication date
February 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
(A and B) Near the basal plane of the cell layer, F-actin tips indicated by the arrows showed the appearance of cryptic lamellipodia. For both EJ and HCT 116, p53 null cells showed reduced appearance of the cryptic lamellipodia. (C) F-actin intensity for EJ p53-on cells are 1.5±0.2 times than that for EJ p53-off cells. (D) F-actin intensity for HCT 116 p53+/+ cells are 1.8±0.4 times higher than that for HCT 116 p53-/- cells. Scale bar, 100μm.</p
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