MOESM4 of CIB1 depletion with docetaxel or TRAIL enhances triple-negative breast cancer cell death

Additional file 4: Figure S3. CIB1 depletion plus docetaxel activates death receptor-mediated apoptosis in other TNBC cells. Caspase-8 activation is observed in TNBC cell lines treated with the combination of CIB1 depletion and the indicated concentrations of docetaxel. Control and CIB1-depleted a) MDA-468 (n=3) and b) MDA-231 (n=3) cells were treated with either vehicle (DMSO) or docetaxel as in Additional file 2: Figure S1B. Representative Western blot showing cleaved caspase-8 and GAPDH (lower panel, n=3)