(A) Western blot on control, germ cell cKO and Sertoli cell cKO testes, 6 months after birth. DMXL2 protein was detected in control and Sertoli cell cKO testes. (B, C) RT-qPCR analyses of Dmxl2 transcript levels in the testes of mice of the four different genotypes (7 weeks after birth), with Dmxl2 mRNA quantification based on the amplification of exon 7. Dmxl2 transcript levels are much lower in germ cell cKO testes (B and C), but a complete abolition of the expression of this gene was observed only in dcKO testes (C). Asterisks indicate significant differences between genotypes (pValue<0.05).</p
<p>(A) Mad2l2 mRNA expression in adult murine organs and E14.5 embryos. For an actin loading control...
<p>(<b>a</b>) Western blot analysis of KATNAL2 protein expression in whole testis homogenates from <...
Transfer of certain Mus domesticus-derived Y chromosomes (Sry(DOM) alleles, e.g., Sry(POS) and Sry(A...
(A)Dmxl2 mRNA levels were assessed by RT-qPCR during ovarian (white bars) and testicular (black bars...
International audienceGonad differentiation is a crucial step conditioning the future fertility of i...
Gonad differentiation is a crucial step conditioning the future fertility of individuals and most of...
(A) The top-ranking functional networks according to IPA. Thirty of the 161 genes upregulated in Dmx...
(A) X-gal staining of E14.5 embryos and P0 heads. Staining revealed a restriction of Dmxl2 expressio...
(A) Immunohistochemistry was used to detect cCasp-3 (brown) in control and dcKO testes. (B) The cCas...
Background: Experiments were designed to identify the developmental expression and function of the D...
(A) Genetic construct. Dmxl2 is located on chromosome 15 in mice, and encodes 9 isoforms, 4 of which...
<p><b>A–E.</b> Analysis of total testis gene expression patterns of <i>Smc1β<sup>−/−</sup></i> mice ...
<p><b>(</b>A) A total of 10 μg of total RNA was extracted from each of the adult (4-month-old; lane ...
<p><b>Copyright information:</b></p><p>Taken from "Loss of spermatogonia and wide-spread DNA methyla...
<p>(A). Positions of primers used in RT-PCRs. (B) Slxl1 mRNA was exclusively expressed in mouse test...
<p>(A) Mad2l2 mRNA expression in adult murine organs and E14.5 embryos. For an actin loading control...
<p>(<b>a</b>) Western blot analysis of KATNAL2 protein expression in whole testis homogenates from <...
Transfer of certain Mus domesticus-derived Y chromosomes (Sry(DOM) alleles, e.g., Sry(POS) and Sry(A...
(A)Dmxl2 mRNA levels were assessed by RT-qPCR during ovarian (white bars) and testicular (black bars...
International audienceGonad differentiation is a crucial step conditioning the future fertility of i...
Gonad differentiation is a crucial step conditioning the future fertility of individuals and most of...
(A) The top-ranking functional networks according to IPA. Thirty of the 161 genes upregulated in Dmx...
(A) X-gal staining of E14.5 embryos and P0 heads. Staining revealed a restriction of Dmxl2 expressio...
(A) Immunohistochemistry was used to detect cCasp-3 (brown) in control and dcKO testes. (B) The cCas...
Background: Experiments were designed to identify the developmental expression and function of the D...
(A) Genetic construct. Dmxl2 is located on chromosome 15 in mice, and encodes 9 isoforms, 4 of which...
<p><b>A–E.</b> Analysis of total testis gene expression patterns of <i>Smc1β<sup>−/−</sup></i> mice ...
<p><b>(</b>A) A total of 10 μg of total RNA was extracted from each of the adult (4-month-old; lane ...
<p><b>Copyright information:</b></p><p>Taken from "Loss of spermatogonia and wide-spread DNA methyla...
<p>(A). Positions of primers used in RT-PCRs. (B) Slxl1 mRNA was exclusively expressed in mouse test...
<p>(A) Mad2l2 mRNA expression in adult murine organs and E14.5 embryos. For an actin loading control...
<p>(<b>a</b>) Western blot analysis of KATNAL2 protein expression in whole testis homogenates from <...
Transfer of certain Mus domesticus-derived Y chromosomes (Sry(DOM) alleles, e.g., Sry(POS) and Sry(A...