Time course of stepwise selection of IVM tolerance in wild-type and <i>nhr-8</i>-deficient <i>C</i>. <i>elegans</i> strains.
- Cécile Ménez (300702)
- Mélanie Alberich (6331418)
- Elise Courtot (517377)
- Fabrice Guegnard (6331421)
- Alexandra Blanchard (260390)
- Hugo Aguilaniu (228029)
- Anne Lespine (300705)
Publication date
February 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
Comparison between the development kinetics of acquired resistance to IVM in wild-type N2 Bristol (solid line) and nhr-8-(ok186) (dashed line) C. elegans strains following stepwise exposure to IVM. Worms, cultured on Nematode Growth Medium plates containing IVM, were transferred to NGM plates containing higher doses of MLs when able to survive and reproduce. The period of 35 weeks corresponds approximately to 60 generations for each strain. Data representative of three separate experiments.</p
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