Additional file 3: of First-in-class positron emission tomography tracer for the glucagon receptor

Additional file 1: of A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling

Edward Ballister (4773627)
Jessica Rodgers (4773630)
Franck Martial (725711)
Robert Lucas (3019824)

January 2018

Curve-fitting results for pooled dose–response data shown in Fig. 1d. For each GPCR/G protein combin...

Post-imaging biodistribution data (%ID/g) for 68Ga-Galmydar in rats treated either with DOX (15mg/kg; 5 days prior to imaging) or vehicle as a control (mean ± SD, n = 3).

Jothilingam Sivapackiam (651201)
Shivesh Kabra (6729161)
Sylvia Speidel (6729164)
Monica Sharma (1764358)
Richard Laforest (6729167)
Amber Salter (4582774)
Michael P. Rettig (6729170)
Vijay Sharma (651200)

May 2019

Using Wilcoxon 2-sample tests, and one-sided, the p values were obtained for uptake in each organ (B...

Assessment of S Values in Stylized and Voxel-Based Rat Models for Positron-Emitting Radionuclides

Xie, Tianwu
Zaidi, Habib

October 2013

Positron emission tomography (PET) is a powerful tool in small animal research, enabling noninvasive...

Additional file 4: of First-in-class positron emission tomography tracer for the glucagon receptor

Irina Velikyan (492162)
Torsten Haack (2670532)
Martin Bossart (2456944)
Andreas Evers (1585204)
Iina Laitinen (6370682)
Philip Larsen (6370685)
Oliver Plettenburg (481045)
Lars Johansson (219399)
Stefan Pierrou (6370688)
Michael Wagner (56165)
Olof Eriksson (50033)

February 2019

Table S2. Biodistribution of [68Ga]Ga-DO3A-S02-GCG over 180âmin in rat. Individual values of each ...

Additional file 2: of First-in-class positron emission tomography tracer for the glucagon receptor

Irina Velikyan (492162)
Torsten Haack (2670532)
Martin Bossart (2456944)
Andreas Evers (1585204)
Iina Laitinen (6370682)
Philip Larsen (6370685)
Oliver Plettenburg (481045)
Lars Johansson (219399)
Stefan Pierrou (6370688)
Michael Wagner (56165)
Olof Eriksson (50033)

February 2019

Figure S1. A typical UV (blue)-Radio (red)-chromatogram of [68Ga]Ga-DO3A-S01-GCG at the end of the s...

First-in-class positron emission tomography tracer for the glucagon receptor.

Velikyan, I.
Haack, T.
Bossart, M.
Evers, A.
Laitinen, I.
Larsen, P.
Plettenburg, O.
Johansson, L.
Pierrou, S.
Wagner, M.
Eriksson, O.

January 2019

The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially...

First-in-class positron emission tomography tracer for the glucagon receptor

Velikyan, Irina
Haack, Torsten
Bossart, Martin
Evers, Andreas
Laitinen, Iina
Larsen, Philip
Plettenburg, Oliver
Johansson, Lars
Pierrou, Stefan
Wagner, Michael
Eriksson, Olof

January 2019

The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially...

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates

Eriksson, Olof
Velikyan, Irina
Haack, Torsten
Bossart, Martin
Evers, Andreas
Laitinen, Iina
Larsen, Philip J.
Plettenburg, Oliver
Takano, Akihiro
Halldin, Christer
Antoni, Gunnar
Johansson, Lars
Pierrou, Stefan
Wagner, Michael

January 2019

The glucagon receptor (GCGR) is an emerging target in anti-diabetic therapy. Reliable biomarkers for...

Additional file 1: of Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results

Mathias Kranz (3069744)
Bernhard Sattler (3765586)
Solveig Tiepolt (3765589)
Stephan Wilke (3765583)
Winnie Deuther-Conrad (1399171)
Cornelius Donat (3765580)
Steffen Fischer (1795702)
Marianne Patt (3765592)
Andreas Schildan (3765595)
Jörg Patt (3765598)
René Smits (3765577)
Alexander Hoepping (3010434)
Jörg Steinbach (3765601)
Osama Sabri (283453)
Peter Brust (1399174)

October 2016

Figures S1 to S6 and Tables S1 to S3. Figure S1. PET images (maximum intensity projection, MIP) 1 h ...

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.

Eriksson, O.
Velikyan, I.
Haack, T.
Bossart, M.
Evers, A.
Laitinen, I.
Larsen, P.J.
Plettenburg, O.
Takano, A.
Halldin, C.
Antoni, G.
Johansson, L.
Pierrou, S.
Wagner, M.

January 2019

The glucagon receptor (GCGR) is an emerging target in anti-diabetic therapy. Reliable biomarkers for...

Additional file 2: Figure S1. of Expression dynamics and relations with nearby genes of rat transposable elements across 11 organs, 4 developmental stages and both sexes

Yongcheng Dong (429138)
Ziyan Huang (3863497)
Qifan Kuang (624438)
Zhining Wen (226349)
Zhibin Liu (4399105)
Yizhou Li (226344)
Yi Yang (116183)
Menglong Li (226358)

August 2017

The distribution of pair-wise Pearson correlation coefficient (PCC) in each organ. X-axis represents...

Additional file 1: Figure S1. of Lack of neuroinflammation in the HIV-1 transgenic rat: an [18F]-DPA714 PET imaging study

Dianne Lee (3437792)
Xuyi Yue (1337811)
Wael Ibrahim (3437783)
Margaret Lentz (3437780)
Kristin Peterson (3437789)
Elaine Jagoda (3017037)
Michael Kassiou (281876)
Dragan Maric (91058)
William Reid (3437786)
Dima Hammoud (746658)

September 2015

[18F]DPA-714 PET time-activity curves over 60Â min derived from the caudate and hippocampus of 3-, 6...

Additional file 1: of Diffusion-weighted magnetic resonance imaging using a preclinical 1 T PET/MRI in healthy and tumor-bearing rats

Jakob Albrecht (6393776)
Dietrich Polenz (6393779)
Anja Kühl (23410)
Julian Rogasch (5173727)
Annekatrin Leder (6393782)
Igor Sauer (389103)
Magor Babos (336070)
Gabor Mócsai (6393785)
Nicola Beindorff (6393788)
Ingo Steffen (51774)
Winfried Brenner (636428)
Eva Koziolek (4329832)

February 2019

Immunohistochemic staining of liver parenchyma from tumor-bearing rats 1–4 and one healthy rat. (DOC...

Additional file 1: of Intra-individual comparison of 68Ga-PSMA-11 and 18F-DCFPyL normal-organ biodistribution

GonĂ§alo Ferreira (6705008)
Amir Iravani (4710744)
Michael Hofman (4054939)
Rodney Hicks (4054942)

May 2019

Table S1. Correlation between clinical/protocol variables and each tracersâ quantitative uptake in...

Additional file 2: Figure S2. of The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

Juliana Maynard (3761899)
Sally-Ann Emmas (3761905)
Francois-Xavier Blé (3761908)
Hervé Barjat (3761902)
Emily Lawrie (3761893)
Urs Hancox (2123695)
Deborah Oakes (3761896)
Urszula Polanska (3761890)
Simon Barry (255454)

August 2016

A single dose of AZD8186 (50 mg/kg) results in a non-uniform modulation of biomarkers associated wit...

Additional file 1: of A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling

Edward Ballister (4773627)
Jessica Rodgers (4773630)
Franck Martial (725711)
Robert Lucas (3019824)

January 2018

Curve-fitting results for pooled dose–response data shown in Fig. 1d. For each GPCR/G protein combin...

Post-imaging biodistribution data (%ID/g) for 68Ga-Galmydar in rats treated either with DOX (15mg/kg; 5 days prior to imaging) or vehicle as a control (mean ± SD, n = 3).

Jothilingam Sivapackiam (651201)
Shivesh Kabra (6729161)
Sylvia Speidel (6729164)
Monica Sharma (1764358)
Richard Laforest (6729167)
Amber Salter (4582774)
Michael P. Rettig (6729170)
Vijay Sharma (651200)

May 2019

Using Wilcoxon 2-sample tests, and one-sided, the p values were obtained for uptake in each organ (B...

Assessment of S Values in Stylized and Voxel-Based Rat Models for Positron-Emitting Radionuclides

Xie, Tianwu
Zaidi, Habib

October 2013

Positron emission tomography (PET) is a powerful tool in small animal research, enabling noninvasive...

Additional file 4: of First-in-class positron emission tomography tracer for the glucagon receptor

Irina Velikyan (492162)
Torsten Haack (2670532)
Martin Bossart (2456944)
Andreas Evers (1585204)
Iina Laitinen (6370682)
Philip Larsen (6370685)
Oliver Plettenburg (481045)
Lars Johansson (219399)
Stefan Pierrou (6370688)
Michael Wagner (56165)
Olof Eriksson (50033)

February 2019

Table S2. Biodistribution of [68Ga]Ga-DO3A-S02-GCG over 180âmin in rat. Individual values of each ...

Additional file 2: of First-in-class positron emission tomography tracer for the glucagon receptor

Irina Velikyan (492162)
Torsten Haack (2670532)
Martin Bossart (2456944)
Andreas Evers (1585204)
Iina Laitinen (6370682)
Philip Larsen (6370685)
Oliver Plettenburg (481045)
Lars Johansson (219399)
Stefan Pierrou (6370688)
Michael Wagner (56165)
Olof Eriksson (50033)

February 2019

Figure S1. A typical UV (blue)-Radio (red)-chromatogram of [68Ga]Ga-DO3A-S01-GCG at the end of the s...

First-in-class positron emission tomography tracer for the glucagon receptor.

Velikyan, I.
Haack, T.
Bossart, M.
Evers, A.
Laitinen, I.
Larsen, P.
Plettenburg, O.
Johansson, L.
Pierrou, S.
Wagner, M.
Eriksson, O.

January 2019

The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially...

First-in-class positron emission tomography tracer for the glucagon receptor

Velikyan, Irina
Haack, Torsten
Bossart, Martin
Evers, Andreas
Laitinen, Iina
Larsen, Philip
Plettenburg, Oliver
Johansson, Lars
Pierrou, Stefan
Wagner, Michael
Eriksson, Olof

January 2019

The glucagon receptor (GCGR) is emerging as an important target in anti-diabetic therapy, especially...

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates

Eriksson, Olof
Velikyan, Irina
Haack, Torsten
Bossart, Martin
Evers, Andreas
Laitinen, Iina
Larsen, Philip J.
Plettenburg, Oliver
Takano, Akihiro
Halldin, Christer
Antoni, Gunnar
Johansson, Lars
Pierrou, Stefan
Wagner, Michael

January 2019

The glucagon receptor (GCGR) is an emerging target in anti-diabetic therapy. Reliable biomarkers for...

Additional file 1: of Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results

Mathias Kranz (3069744)
Bernhard Sattler (3765586)
Solveig Tiepolt (3765589)
Stephan Wilke (3765583)
Winnie Deuther-Conrad (1399171)
Cornelius Donat (3765580)
Steffen Fischer (1795702)
Marianne Patt (3765592)
Andreas Schildan (3765595)
Jörg Patt (3765598)
René Smits (3765577)
Alexander Hoepping (3010434)
Jörg Steinbach (3765601)
Osama Sabri (283453)
Peter Brust (1399174)

October 2016

Figures S1 to S6 and Tables S1 to S3. Figure S1. PET images (maximum intensity projection, MIP) 1 h ...

Assessment of glucagon receptor occupancy by Positron Emission Tomography in non-human primates.

Eriksson, O.
Velikyan, I.
Haack, T.
Bossart, M.
Evers, A.
Laitinen, I.
Larsen, P.J.
Plettenburg, O.
Takano, A.
Halldin, C.
Antoni, G.
Johansson, L.
Pierrou, S.
Wagner, M.

January 2019

The glucagon receptor (GCGR) is an emerging target in anti-diabetic therapy. Reliable biomarkers for...

Additional file 2: Figure S1. of Expression dynamics and relations with nearby genes of rat transposable elements across 11 organs, 4 developmental stages and both sexes

Yongcheng Dong (429138)
Ziyan Huang (3863497)
Qifan Kuang (624438)
Zhining Wen (226349)
Zhibin Liu (4399105)
Yizhou Li (226344)
Yi Yang (116183)
Menglong Li (226358)

August 2017

The distribution of pair-wise Pearson correlation coefficient (PCC) in each organ. X-axis represents...

Additional file 1: Figure S1. of Lack of neuroinflammation in the HIV-1 transgenic rat: an [18F]-DPA714 PET imaging study

Dianne Lee (3437792)
Xuyi Yue (1337811)
Wael Ibrahim (3437783)
Margaret Lentz (3437780)
Kristin Peterson (3437789)
Elaine Jagoda (3017037)
Michael Kassiou (281876)
Dragan Maric (91058)
William Reid (3437786)
Dima Hammoud (746658)

September 2015

[18F]DPA-714 PET time-activity curves over 60Â min derived from the caudate and hippocampus of 3-, 6...

Additional file 1: of Diffusion-weighted magnetic resonance imaging using a preclinical 1 T PET/MRI in healthy and tumor-bearing rats

Jakob Albrecht (6393776)
Dietrich Polenz (6393779)
Anja Kühl (23410)
Julian Rogasch (5173727)
Annekatrin Leder (6393782)
Igor Sauer (389103)
Magor Babos (336070)
Gabor Mócsai (6393785)
Nicola Beindorff (6393788)
Ingo Steffen (51774)
Winfried Brenner (636428)
Eva Koziolek (4329832)

February 2019

Immunohistochemic staining of liver parenchyma from tumor-bearing rats 1–4 and one healthy rat. (DOC...

Additional file 1: of Intra-individual comparison of 68Ga-PSMA-11 and 18F-DCFPyL normal-organ biodistribution

GonĂ§alo Ferreira (6705008)
Amir Iravani (4710744)
Michael Hofman (4054939)
Rodney Hicks (4054942)

May 2019

Table S1. Correlation between clinical/protocol variables and each tracersâ quantitative uptake in...

Additional file 2: Figure S2. of The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

Juliana Maynard (3761899)
Sally-Ann Emmas (3761905)
Francois-Xavier Blé (3761908)
Hervé Barjat (3761902)
Emily Lawrie (3761893)
Urs Hancox (2123695)
Deborah Oakes (3761896)
Urszula Polanska (3761890)
Simon Barry (255454)

August 2016

A single dose of AZD8186 (50 mg/kg) results in a non-uniform modulation of biomarkers associated wit...

Additional file 1: of A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling

Edward Ballister (4773627)
Jessica Rodgers (4773630)
Franck Martial (725711)
Robert Lucas (3019824)

January 2018

Curve-fitting results for pooled dose–response data shown in Fig. 1d. For each GPCR/G protein combin...

Post-imaging biodistribution data (%ID/g) for 68Ga-Galmydar in rats treated either with DOX (15mg/kg; 5 days prior to imaging) or vehicle as a control (mean ± SD, n = 3).

Jothilingam Sivapackiam (651201)
Shivesh Kabra (6729161)
Sylvia Speidel (6729164)
Monica Sharma (1764358)
Richard Laforest (6729167)
Amber Salter (4582774)
Michael P. Rettig (6729170)
Vijay Sharma (651200)

May 2019

Using Wilcoxon 2-sample tests, and one-sided, the p values were obtained for uptake in each organ (B...

Assessment of S Values in Stylized and Voxel-Based Rat Models for Positron-Emitting Radionuclides

Xie, Tianwu
Zaidi, Habib

October 2013

Positron emission tomography (PET) is a powerful tool in small animal research, enabling noninvasive...

Additional file 3: of First-in-class positron emission tomography tracer for the glucagon receptor

Abstract

Extracted data

Additional file 3: of First-in-class positron emission tomography tracer for the glucagon receptor

Abstract

Extracted data

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