Additional file 2: of Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas

Figure S1. cAMP and iCa2+ mobilization in response to CTR agonists. A, Characterization of cAMP accumulation (30 min) in WK1 cells in response to stimulation by sCT alone or in presence of 1 μM forskolin. Data are presented as mean + S.E.M. of 3 replicates of a representative experiment. Absence of intracellular calcium mobilization response to sCT and rAMY in WK1 (B), SB2b (C) and PB1(D) cell lines while maintaining robust response to 10 μM ATP and 1 μM ionomycin. Data are presented as peak values of response measured in relative fluorescence units. Data are presented as mean + or - S.E.M. of 3 replicates of a representative experiment. (PDF 907 kb