Additional file 1: of Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

Vessela Vassileva (4056163)
Stephen Stribbling (6381179)
Chris Barnes (265806)
Laurence Carroll (3072045)
Marta Braga (6381182)
Joel Abrahams (6381185)
Kathrin Heinzmann (3762427)
Caroline Haegeman (6381191)
Marion MacFarlane (6381194)
Kathryn Simpson (2173090)
Caroline Dive (421487)
Jamie Honeychurch (6381200)
Timothy Illidge (6381206)
Eric Aboagye (3418220)

Publication date

February 2019

DOI

10.6084/m9.figshare.7744349.v1

Abstract

Figure S1. PET imaging with apoptotic radiotracers. Representative PET images with (A) 18F-ICMT-11 at 6 and 24âh and (B) 18F-ML-10 at 24âh, after doxycycline administration in mice bearing B16ova and B16ovaRevC3 tumours. (PDF 560 kb

Extracted data

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Additional file 1: of Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

Vessela Vassileva (4056163)
Stephen Stribbling (6381179)
Chris Barnes (265806)
Laurence Carroll (3072045)
Marta Braga (6381182)
Joel Abrahams (6381185)
Kathrin Heinzmann (3762427)
Caroline Haegeman (6381191)
Marion MacFarlane (6381194)
Kathryn Simpson (2173090)
Caroline Dive (421487)
Jamie Honeychurch (6381200)
Timothy Illidge (6381206)
Eric Aboagye (3418220)

Open link

Publication date

February 2019

DOI

10.6084/m9.figshare.7744349.v1

Abstract

Extracted data

Jinzi Zheng (428432)
Stephan Klinz (3761923)
Raquel De Souza (2233627)
Jonathan Fitzgerald (3761920)
David A. Jaffray (141216)

October 2015

Figures S1–S3. Figure S1. Mean FAZA administration dose (MBq/g) calculated for animals belonging to ...

Additional file 3: of Evaluation of prognostic models developed using standardised image features from different PET automated segmentation methods

Craig Parkinson (5090819)
Kieran Foley (5090822)
Philip Whybra (5090825)
Robert Hills (3685870)
Ashley Roberts (4171666)
Chris Marshall (5090828)
John Staffurth (4595989)
Emiliano Spezi (835799)

April 2018

Correlation of radiomic features and the delineated Metabolic Tumour Volume. (DOCX 2375Â kb

Additional file 8: of In vivo imaging of the immune response upon systemic RNA cancer vaccination by FDG-PET

Stefanie Pektor (493377)
Lina Hilscher (5636087)
Kerstin Walzer (5636090)
Isabelle Miederer (5636093)
Nicole Bausbacher (1642201)
Carmen Loquai (103597)
Mathias Schreckenberger (582710)
Ugur Sahin (133198)
Mustafa Diken (133183)
Matthias Miederer (372618)

August 2018

Figure S8. Balb/c mice were immunized two times (d0 and d7) with 20 μg gp70-LPX, liposomes alone, gp...

Additional file 3: Figure S3. of The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

Juliana Maynard (3761899)
Sally-Ann Emmas (3761905)
Francois-Xavier Blé (3761908)
Hervé Barjat (3761902)
Emily Lawrie (3761893)
Urs Hancox (2123695)
Deborah Oakes (3761896)
Urszula Polanska (3761890)
Simon Barry (255454)

August 2016

A single dose of AZD8186 (50 mg/kg) results in only limited apoptotic cell death and upregulatedcell...

Additional file 1: of Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results

Mathias Kranz (3069744)
Bernhard Sattler (3765586)
Solveig Tiepolt (3765589)
Stephan Wilke (3765583)
Winnie Deuther-Conrad (1399171)
Cornelius Donat (3765580)
Steffen Fischer (1795702)
Marianne Patt (3765592)
Andreas Schildan (3765595)
Jörg Patt (3765598)
René Smits (3765577)
Alexander Hoepping (3010434)
Jörg Steinbach (3765601)
Osama Sabri (283453)
Peter Brust (1399174)

October 2016

Figures S1 to S6 and Tables S1 to S3. Figure S1. PET images (maximum intensity projection, MIP) 1 h ...

Additional file 1: Figure S1. of A novel 11C-labeled thymidine analog, [11C]AZT, for tumor imaging by positron emission tomography

Tsuyoshi Tahara (78341)
Zhouen Zhang (3762316)
Masahiro Ohno (3762325)
Yukako Hirao (3762322)
Nami Hosaka (3762319)
Hisashi Doi (1580995)
Masaaki Suzuki (209213)
Hirotaka Onoe (15243)

September 2015

PET images of C6 and HeLa tumor-bearing mice between 30 and 60 min after injection of 50 MBq of [11C...

Additional file 2: of Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis

Janine Schniering (4048954)
Li Guo (171454)
Matthias Brunner (5639456)
Roger Schibli (162152)
Shuang Ye (247348)
Oliver Distler (36405)
Martin Béhé (2717173)
Britta Maurer (4048951)

August 2018

Semi-quantification of the number of leucocytes, epithelial cells, myofibroblasts and endothelial ce...

Additional file 5: of MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer

Yoshimi Greer (6374504)
Samuel Gilbert (6374507)
Brunilde Gril (202357)
Rajesh Narwal (4425985)
Danielle Peacock Brooks (6374510)
David Tice (3173028)
Patricia Steeg (6374513)
Stanley Lipkowitz (253942)

February 2019

Histology analysis of extra MFP tumor developed in later stage in a mouse treated with MEDI3039. (A)...

Additional file 1: Figure S1. of 18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis

Sara Belloli (2434309)
Lucia Zanotti (262872)
Valentina Murtaj (4823409)
Cristina Mazzon (344063)
Giuseppe Di Grigoli (4823418)
Cristina Monterisi (4823421)
Valeria Masiello (4823412)
Leonardo Iaccarino (700272)
Andrea Cappelli (1546723)
Pietro Poliani (4823415)
Letterio Politi (4823403)
Rosa Moresco (4823406)

February 2018

PET and MRI images of EAE mice at 14 days p.i. In vivo PET and MRI representative images of three of...

Additional file 1: Figure S1. of ERK mediated upregulation of death receptor 5 overcomes the lack of p53 functionality in the diaminothiazole DAT1 induced apoptosis in colon cancer models: efficiency of DAT1 in Ras-Raf mutated cells

Reshma Thamkachy (3767449)
Rohith Kumar (465288)
K. Rajasekharan (3767446)
Suparna Sengupta (465292)

March 2016

Comparison of apoptosis in HCT116 and HCT116 p53 −/− cells treated with vinblastine : Cells were tre...

Additional file 5: of Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model

Zhao-Hui Jin (32111)
Atsushi Tsuji (5424743)
Mélissa Degardin (5424740)
Aya Sugyo (389882)
Yukie Yoshii (416882)
Kotaro Nagatsu (399964)
Ming-Rong Zhang (136828)
Yasuhisa Fujibayashi (416891)
Pascal Dumy (8679)
Didier Boturyn (32114)
Tatsuya Higashi (5424737)

June 2018

Tumor growth curves (a) and body weight changes (b) of the same set of experimental groups as descri...

Additional file 4: of Leveraging PET to image folate receptor α therapy of an antibody-drug conjugate

Christian Brand (1326921)
Ahmad Sadique (5696162)
Jacob Houghton (5696165)
Kishore Gangangari (5696168)
Jose Ponte (5696171)
Jason Lewis (4638244)
Naga Pillarsetty (5696174)
Jason Konner (5696177)
Thomas Reiner (848165)

August 2018

Figure S4. Serial PET imaging at 4 h, 24 h, 48 h, and 72 h post-administration of [89Zr]Zr-DFO-M9346...

Additional file 2: Figure S2. of The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

Juliana Maynard (3761899)
Sally-Ann Emmas (3761905)
Francois-Xavier Blé (3761908)
Hervé Barjat (3761902)
Emily Lawrie (3761893)
Urs Hancox (2123695)
Deborah Oakes (3761896)
Urszula Polanska (3761890)
Simon Barry (255454)

August 2016

A single dose of AZD8186 (50 mg/kg) results in a non-uniform modulation of biomarkers associated wit...

Additional file 1: of Effects of a novel peptide Ac-SDKP in radiation-induced coronary endothelial damage and resting myocardial blood flow

Umesh Sharma (5028707)
Swati Sonkawade (5209571)
Andrew Baird (344174)
Min Chen (147733)
Shirley Xu (6101000)
Sandra Sexton (6101003)
Anurag Singh (283570)
Adrienne Groman (139809)
Steven Turowski (2298058)
Joseph Spernyak (6101006)
Supriya Mahajan (5209577)
Saraswati Pokharel (5209574)

December 2018

Figure S1. Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining for apoptos...

Additional file 1: of Longitudinal tumor hypoxia imaging with [18F]FAZA-PET provides early prediction of nanoliposomal irinotecan (nal-IRI) treatment activity

Jinzi Zheng (428432)
Stephan Klinz (3761923)
Raquel De Souza (2233627)
Jonathan Fitzgerald (3761920)
David A. Jaffray (141216)

October 2015

Figures S1–S3. Figure S1. Mean FAZA administration dose (MBq/g) calculated for animals belonging to ...

Additional file 3: of Evaluation of prognostic models developed using standardised image features from different PET automated segmentation methods

Craig Parkinson (5090819)
Kieran Foley (5090822)
Philip Whybra (5090825)
Robert Hills (3685870)
Ashley Roberts (4171666)
Chris Marshall (5090828)
John Staffurth (4595989)
Emiliano Spezi (835799)

April 2018

Correlation of radiomic features and the delineated Metabolic Tumour Volume. (DOCX 2375Â kb

Additional file 8: of In vivo imaging of the immune response upon systemic RNA cancer vaccination by FDG-PET

Stefanie Pektor (493377)
Lina Hilscher (5636087)
Kerstin Walzer (5636090)
Isabelle Miederer (5636093)
Nicole Bausbacher (1642201)
Carmen Loquai (103597)
Mathias Schreckenberger (582710)
Ugur Sahin (133198)
Mustafa Diken (133183)
Matthias Miederer (372618)

August 2018

Figure S8. Balb/c mice were immunized two times (d0 and d7) with 20 μg gp70-LPX, liposomes alone, gp...

Additional file 3: Figure S3. of The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

Juliana Maynard (3761899)
Sally-Ann Emmas (3761905)
Francois-Xavier Blé (3761908)
Hervé Barjat (3761902)
Emily Lawrie (3761893)
Urs Hancox (2123695)
Deborah Oakes (3761896)
Urszula Polanska (3761890)
Simon Barry (255454)

August 2016

A single dose of AZD8186 (50 mg/kg) results in only limited apoptotic cell death and upregulatedcell...

Additional file 1: of Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results

Mathias Kranz (3069744)
Bernhard Sattler (3765586)
Solveig Tiepolt (3765589)
Stephan Wilke (3765583)
Winnie Deuther-Conrad (1399171)
Cornelius Donat (3765580)
Steffen Fischer (1795702)
Marianne Patt (3765592)
Andreas Schildan (3765595)
Jörg Patt (3765598)
René Smits (3765577)
Alexander Hoepping (3010434)
Jörg Steinbach (3765601)
Osama Sabri (283453)
Peter Brust (1399174)

October 2016

Figures S1 to S6 and Tables S1 to S3. Figure S1. PET images (maximum intensity projection, MIP) 1 h ...

Additional file 1: Figure S1. of A novel 11C-labeled thymidine analog, [11C]AZT, for tumor imaging by positron emission tomography

Tsuyoshi Tahara (78341)
Zhouen Zhang (3762316)
Masahiro Ohno (3762325)
Yukako Hirao (3762322)
Nami Hosaka (3762319)
Hisashi Doi (1580995)
Masaaki Suzuki (209213)
Hirotaka Onoe (15243)

September 2015

PET images of C6 and HeLa tumor-bearing mice between 30 and 60 min after injection of 50 MBq of [11C...

Additional file 2: of Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis

Janine Schniering (4048954)
Li Guo (171454)
Matthias Brunner (5639456)
Roger Schibli (162152)
Shuang Ye (247348)
Oliver Distler (36405)
Martin Béhé (2717173)
Britta Maurer (4048951)

August 2018

Semi-quantification of the number of leucocytes, epithelial cells, myofibroblasts and endothelial ce...

Yoshimi Greer (6374504)
Samuel Gilbert (6374507)
Brunilde Gril (202357)
Rajesh Narwal (4425985)
Danielle Peacock Brooks (6374510)
David Tice (3173028)
Patricia Steeg (6374513)
Stanley Lipkowitz (253942)

February 2019

Histology analysis of extra MFP tumor developed in later stage in a mouse treated with MEDI3039. (A)...

Additional file 1: Figure S1. of 18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis

Sara Belloli (2434309)
Lucia Zanotti (262872)
Valentina Murtaj (4823409)
Cristina Mazzon (344063)
Giuseppe Di Grigoli (4823418)
Cristina Monterisi (4823421)
Valeria Masiello (4823412)
Leonardo Iaccarino (700272)
Andrea Cappelli (1546723)
Pietro Poliani (4823415)
Letterio Politi (4823403)
Rosa Moresco (4823406)

February 2018

PET and MRI images of EAE mice at 14 days p.i. In vivo PET and MRI representative images of three of...

Reshma Thamkachy (3767449)
Rohith Kumar (465288)
K. Rajasekharan (3767446)
Suparna Sengupta (465292)

March 2016

Comparison of apoptosis in HCT116 and HCT116 p53 −/− cells treated with vinblastine : Cells were tre...

Zhao-Hui Jin (32111)
Atsushi Tsuji (5424743)
Mélissa Degardin (5424740)
Aya Sugyo (389882)
Yukie Yoshii (416882)
Kotaro Nagatsu (399964)
Ming-Rong Zhang (136828)
Yasuhisa Fujibayashi (416891)
Pascal Dumy (8679)
Didier Boturyn (32114)
Tatsuya Higashi (5424737)

June 2018

Tumor growth curves (a) and body weight changes (b) of the same set of experimental groups as descri...

Additional file 4: of Leveraging PET to image folate receptor α therapy of an antibody-drug conjugate

Christian Brand (1326921)
Ahmad Sadique (5696162)
Jacob Houghton (5696165)
Kishore Gangangari (5696168)
Jose Ponte (5696171)
Jason Lewis (4638244)
Naga Pillarsetty (5696174)
Jason Konner (5696177)
Thomas Reiner (848165)

August 2018

Figure S4. Serial PET imaging at 4 h, 24 h, 48 h, and 72 h post-administration of [89Zr]Zr-DFO-M9346...

Additional file 2: Figure S2. of The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

Juliana Maynard (3761899)
Sally-Ann Emmas (3761905)
Francois-Xavier Blé (3761908)
Hervé Barjat (3761902)
Emily Lawrie (3761893)
Urs Hancox (2123695)
Deborah Oakes (3761896)
Urszula Polanska (3761890)
Simon Barry (255454)

August 2016

A single dose of AZD8186 (50 mg/kg) results in a non-uniform modulation of biomarkers associated wit...

Additional file 1: of Effects of a novel peptide Ac-SDKP in radiation-induced coronary endothelial damage and resting myocardial blood flow

Umesh Sharma (5028707)
Swati Sonkawade (5209571)
Andrew Baird (344174)
Min Chen (147733)
Shirley Xu (6101000)
Sandra Sexton (6101003)
Anurag Singh (283570)
Adrienne Groman (139809)
Steven Turowski (2298058)
Joseph Spernyak (6101006)
Supriya Mahajan (5209577)
Saraswati Pokharel (5209574)

December 2018

Figure S1. Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining for apoptos...

Additional file 1: of Longitudinal tumor hypoxia imaging with [18F]FAZA-PET provides early prediction of nanoliposomal irinotecan (nal-IRI) treatment activity

Jinzi Zheng (428432)
Stephan Klinz (3761923)
Raquel De Souza (2233627)
Jonathan Fitzgerald (3761920)
David A. Jaffray (141216)

October 2015

Figures S1–S3. Figure S1. Mean FAZA administration dose (MBq/g) calculated for animals belonging to ...

Additional file 3: of Evaluation of prognostic models developed using standardised image features from different PET automated segmentation methods

Craig Parkinson (5090819)
Kieran Foley (5090822)
Philip Whybra (5090825)
Robert Hills (3685870)
Ashley Roberts (4171666)
Chris Marshall (5090828)
John Staffurth (4595989)
Emiliano Spezi (835799)

April 2018

Correlation of radiomic features and the delineated Metabolic Tumour Volume. (DOCX 2375Â kb

Additional file 8: of In vivo imaging of the immune response upon systemic RNA cancer vaccination by FDG-PET

Stefanie Pektor (493377)
Lina Hilscher (5636087)
Kerstin Walzer (5636090)
Isabelle Miederer (5636093)
Nicole Bausbacher (1642201)
Carmen Loquai (103597)
Mathias Schreckenberger (582710)
Ugur Sahin (133198)
Mustafa Diken (133183)
Matthias Miederer (372618)

August 2018

Figure S8. Balb/c mice were immunized two times (d0 and d7) with 20 μg gp70-LPX, liposomes alone, gp...

Additional file 1: of Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

Abstract

Extracted data

Additional file 1: of Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

Abstract

Extracted data

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