Additional file 1: of Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis

Borja Hernández-Breijo (3334722)
Chamaida Plasencia-Rodríguez (627498)
Victoria Navarro-Compán (6385358)
Ana Martínez-Feito (6385361)
Andrea Jochems (6385364)
Eva Kneepkens (6385367)
Gerrit Wolbink (6385370)
Theo Rispens (216183)
Cristina Diego (6385373)
Dora Pascual-Salcedo (310351)
Alejandro Balsa (118675)

Publication date

February 2019

DOI

10.6084/m9.figshare.7750337.v1

Abstract

(i) Association between csDMARDs and clinical response (∆ASDAS≥1.1) or remission (ASDAS<1.3) at one year, stratified for body mass index; (ii) Flowchart of patients included in the present study. (DOCX 46 kb

Extracted data

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Data Protection

Additional file 1: of Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis

Borja Hernández-Breijo (3334722)
Chamaida Plasencia-Rodríguez (627498)
Victoria Navarro-Compán (6385358)
Ana Martínez-Feito (6385361)
Andrea Jochems (6385364)
Eva Kneepkens (6385367)
Gerrit Wolbink (6385370)
Theo Rispens (216183)
Cristina Diego (6385373)
Dora Pascual-Salcedo (310351)
Alejandro Balsa (118675)

Open link

Publication date

February 2019

DOI

10.6084/m9.figshare.7750337.v1

Abstract

Extracted data

Raphael Micheroli (4260031)
Monika Hebeisen (4260037)
Lukas Wildi (4260040)
Pascale Exer (3543695)
Giorgio Tamborrini (3543689)
JĂźrg Bernhard (3543698)
Burkhard MĂśller (4260046)
Pascal Zufferey (4260034)
Michael Nissen (4260043)
Almut Scherer (20370)
Adrian Ciurea (763222)

July 2017

Body height before and after correction for kyphosis by using the occiput-to-wall distance. (DOC 118...

Additional file 1: of Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation

Jiahua Fan (6249098)
Yangqing Liu (289844)
Songping Yin (6249101)
Nixuan Chen (6249104)
Xinxiu Bai (6249110)
Qiuyi Ke (6249113)
Jia Shen (1828945)
Min Xia (307622)

January 2019

Figure S1. The relationship between sdLDL-c/LDL-c ratio and prevalence of MetS. Table S1. Logistic r...

Additional file 1: of Patient-reported outcomes from a randomized phase III trial of sarilumab monotherapy versus adalimumab monotherapy in patients with rheumatoid arthritis

Vibeke Strand (410780)
Laure Gossec (4058521)
Clare Proudfoot (5165081)
Chieh-I Chen (4415830)
Matthew Reaney (5424773)
Sophie Guillonneau (5424776)
Toshio Kimura (5424779)
Janet van Adelsberg (5424782)
Yong Lin (177139)
Erin Mangan (5424785)
Hubert van Hoogstraten (5079860)
Gerd Burmester (52016)

June 2018

Table S1. LSM changes in RAID individual domain scores from baseline to week 24 with sarilumab 200Â ...

Additional file 3: Table S1. of Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis

Raphael Micheroli (4260031)
Monika Hebeisen (4260037)
Lukas Wildi (4260040)
Pascale Exer (3543695)
Giorgio Tamborrini (3543689)
JĂźrg Bernhard (3543698)
Burkhard MĂśller (4260046)
Pascal Zufferey (4260034)
Michael Nissen (4260043)
Almut Scherer (20370)
Adrian Ciurea (763222)

July 2017

Impact of obesity and overweight status on different outcomes after 1Â year of treatment with a firs...

Additional file 1: of Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis

Jordi Gratacós (3442037)
Caridad Pontes (3471266)
Xavier Juanola (3471263)
Jesús Sanz (307823)
Ferran Torres (180848)
Cristina Avendaño (3471260)
Antoni Vallano (3471269)
Gonzalo Calvo (3471257)
Eugenio Miguel (3471254)
Raimon Sanmartí (368935)

January 2019

Table S1. Baseline characteristics, subset with inflammatory biomarkers. Table S2. Baseline predicto...

Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis

Hernández-Breijo, Borja
Plasencia-Rodríguez, Chamaida
Navarro-Compán, Victoria
Martínez-Feito, Ana
Jochems, Andrea
Kneepkens, Eva L.
Wolbink, Gerrit J.
Rispens, Theo
Diego, Cristina
Pascual-Salcedo, Dora
Balsa, Alejandro

February 2019

Background: The aim of our study was to investigate the influence of conventional synthetic disease-...

Additional file 3: of A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable

Alessio Cortellini (6409283)
Melissa Bersanelli (3797482)
Sebastiano Buti (3797485)
Katia Cannita (6409292)
Daniele Santini (222870)
Fabiana Perrone (6409298)
Raffaele Giusti (6409304)
Marcello Tiseo (475209)
Maria Michiara (62208)
Pietro Di Marino (6409310)
Nicola Tinari (350375)
Michele De Tursi (548921)
Federica Zoratto (6409313)
Enzo Veltri (6409316)
Riccardo Marconcini (6409319)
Francesco Malorgio (6409322)
Marco Russano (3148566)
Cecilia Anesi (6409325)
Tea Zeppola (6409328)
Marco Filetti (276152)
Paolo Marchetti (393307)
Andrea Botticelli (3133263)
Gian Antonini Cappellini (6409334)
Federica De Galitiis (6409337)
Maria Vitale (3528125)
Francesca Rastelli (6409340)
Federica Pergolesi (6409343)
Rossana Berardi (477376)
Silvia Rinaldi (2054881)
Marianna Tudini (6409346)
Rosa Silva (485080)
Annagrazia Pireddu (6409349)
Francesco Atzori (4745331)
Rita Chiari (6409352)
Biagio Ricciuti (6409355)
Andrea De Giglio (6409358)
Daniela Iacono (6409361)
Alain Gelibter (6409364)
Mario Occhipinti (3133260)
Alessandro Parisi (6409367)
Giampiero Porzio (6409370)
Maria Fargnoli (6116600)
Paolo Ascierto (3777298)
Corrado Ficorella (6409373)
Clara Natoli (548918)

February 2019

Univariate and multivariate analyses with logistic regression of Objective Response Rate. (DOC 49 kb

Additional file 2: of A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable

Alessio Cortellini (6409283)
Melissa Bersanelli (3797482)
Sebastiano Buti (3797485)
Katia Cannita (6409292)
Daniele Santini (222870)
Fabiana Perrone (6409298)
Raffaele Giusti (6409304)
Marcello Tiseo (475209)
Maria Michiara (62208)
Pietro Di Marino (6409310)
Nicola Tinari (350375)
Michele De Tursi (548921)
Federica Zoratto (6409313)
Enzo Veltri (6409316)
Riccardo Marconcini (6409319)
Francesco Malorgio (6409322)
Marco Russano (3148566)
Cecilia Anesi (6409325)
Tea Zeppola (6409328)
Marco Filetti (276152)
Paolo Marchetti (393307)
Andrea Botticelli (3133263)
Gian Antonini Cappellini (6409334)
Federica De Galitiis (6409337)
Maria Vitale (3528125)
Francesca Rastelli (6409340)
Federica Pergolesi (6409343)
Rossana Berardi (477376)
Silvia Rinaldi (2054881)
Marianna Tudini (6409346)
Rosa Silva (485080)
Annagrazia Pireddu (6409349)
Francesco Atzori (4745331)
Rita Chiari (6409352)
Biagio Ricciuti (6409355)
Andrea De Giglio (6409358)
Daniela Iacono (6409361)
Alain Gelibter (6409364)
Mario Occhipinti (3133260)
Alessandro Parisi (6409367)
Giampiero Porzio (6409370)
Maria Fargnoli (6116600)
Paolo Ascierto (3777298)
Corrado Ficorella (6409373)
Clara Natoli (548918)

February 2019

Immune-related adverse events of any grade and G3/G4 immune-related adverse events. (DOCX 15 kb

Additional file 1: of Association of Metabolic Markers with self-reported osteoarthritis among middle-aged BMI-defined non-obese individuals: a cross-sectional study

Kelsey Collins (5710076)
Behnam Sharif (338153)
Raylene Reimer (3416024)
Claudia Sanmartin (549893)
Walter Herzog (713967)
Rick Chin (352186)
Deborah Marshall (3415802)

September 2018

BMI and body fat percentage classification. The supplementary data provides a summary of the sample ...

Additional file 4: of Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons

Lukas Mangnus (3496604)
Wouter Nieuwenhuis (3496595)
Hanna van Steenbergen (3496592)
Tom Huizinga (3398660)
Monique Reijnierse (3496598)
Annette van der Helm-van Mil (3496601)

October 2016

is a figure showing correlations of BMI with MRI-detected inflammation in inflammatory osteoarthriti...

Additional file 1: of Response of fibroblast growth factor 19 and bile acid synthesis after a body weight-adjusted oral fat tolerance test in overweight and obese NAFLD patients: a non-randomized controlled pilot trial

Dana Friedrich (4642099)
Hanns-Ulrich Marschall (506679)
Frank Lammert (2875)

June 2018

Table S1. Prevalence of comorbidities in overweight (Nâ=â14) and obese (12) NAFLD patients. In o...

Additional file 2: of Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons

Lukas Mangnus (3496604)
Wouter Nieuwenhuis (3496595)
Hanna van Steenbergen (3496592)
Tom Huizinga (3398660)
Monique Reijnierse (3496598)
Annette van der Helm-van Mil (3496601)

October 2016

is a table presenting the ICC for total inflammation score for 30 arthritis patients scored by all f...

Additional file 1: of Exploring the associations between systemic inflammation, obesity and healthy days: a health related quality of life (HRQOL) analysis of NHANES 2005–2008

Jeffrey Wilkins (5596064)
Palash Ghosh (5596067)
Juan Vivar (599734)
Bibhas Chakraborty (5596070)
Sujoy Ghosh (51427)

August 2018

Exploring the associations between systemic inflammation, obesity and healthy days: a health related...

Additional file 1: of One-year risk of serious infection in patients treated with certolizumab pegol as compared with other TNF inhibitors in a real-world setting: data from a national U.S. rheumatoid arthritis registry

Leslie Harrold (2578624)
Heather Litman (3967853)
Katherine Saunders (3967850)
Kimberly Dandreo (4763781)
Bernice Gershenson (4763790)
Jeffrey Greenberg (3502604)
Robert Low (4763784)
Jeffrey Stark (4763793)
Robert Suruki (443240)
Srihari Jaganathan (4763787)
Joel Kremer (3475457)
Mohamed Yassine (4763778)

January 2018

Modified Charlson comorbidity index. Table S1. Other AEs of interest. (PDF 246Â kb

Additional file 2: of Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patientsâimmune-related candidate proteins affected by TNF blocking treatment

Johanna Estelius (4846906)
Johan Lengqvist (555763)
Elena Ossipova (666249)
Helena Idborg (2579896)
Erwan MaĂŽtre (6370364)
Magnus Andersson (236322)
Lou Brundin (221842)
Mohsen Khademi (221840)
Elisabet Svenungsson (70507)
Per-Johan Jakobsson (356891)
Jon Lampa (54464)

February 2019

Figure S1. PLS-DA was performed on proteomic data. Figure S2. Overlap between proteins detected in C...

Additional file 2: Figure S2. of Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis

Raphael Micheroli (4260031)
Monika Hebeisen (4260037)
Lukas Wildi (4260040)
Pascale Exer (3543695)
Giorgio Tamborrini (3543689)
JĂźrg Bernhard (3543698)
Burkhard MĂśller (4260046)
Pascal Zufferey (4260034)
Michael Nissen (4260043)
Almut Scherer (20370)
Adrian Ciurea (763222)

July 2017

Body height before and after correction for kyphosis by using the occiput-to-wall distance. (DOC 118...

Additional file 1: of Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation

Jiahua Fan (6249098)
Yangqing Liu (289844)
Songping Yin (6249101)
Nixuan Chen (6249104)
Xinxiu Bai (6249110)
Qiuyi Ke (6249113)
Jia Shen (1828945)
Min Xia (307622)

January 2019

Figure S1. The relationship between sdLDL-c/LDL-c ratio and prevalence of MetS. Table S1. Logistic r...

Additional file 1: of Patient-reported outcomes from a randomized phase III trial of sarilumab monotherapy versus adalimumab monotherapy in patients with rheumatoid arthritis

Vibeke Strand (410780)
Laure Gossec (4058521)
Clare Proudfoot (5165081)
Chieh-I Chen (4415830)
Matthew Reaney (5424773)
Sophie Guillonneau (5424776)
Toshio Kimura (5424779)
Janet van Adelsberg (5424782)
Yong Lin (177139)
Erin Mangan (5424785)
Hubert van Hoogstraten (5079860)
Gerd Burmester (52016)

June 2018

Table S1. LSM changes in RAID individual domain scores from baseline to week 24 with sarilumab 200Â ...

Additional file 3: Table S1. of Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis

Raphael Micheroli (4260031)
Monika Hebeisen (4260037)
Lukas Wildi (4260040)
Pascale Exer (3543695)
Giorgio Tamborrini (3543689)
JĂźrg Bernhard (3543698)
Burkhard MĂśller (4260046)
Pascal Zufferey (4260034)
Michael Nissen (4260043)
Almut Scherer (20370)
Adrian Ciurea (763222)

July 2017

Impact of obesity and overweight status on different outcomes after 1Â year of treatment with a firs...

Additional file 1: of Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis

Jordi Gratacós (3442037)
Caridad Pontes (3471266)
Xavier Juanola (3471263)
Jesús Sanz (307823)
Ferran Torres (180848)
Cristina Avendaño (3471260)
Antoni Vallano (3471269)
Gonzalo Calvo (3471257)
Eugenio Miguel (3471254)
Raimon Sanmartí (368935)

January 2019

Table S1. Baseline characteristics, subset with inflammatory biomarkers. Table S2. Baseline predicto...

Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis

Hernández-Breijo, Borja
Plasencia-Rodríguez, Chamaida
Navarro-Compán, Victoria
Martínez-Feito, Ana
Jochems, Andrea
Kneepkens, Eva L.
Wolbink, Gerrit J.
Rispens, Theo
Diego, Cristina
Pascual-Salcedo, Dora
Balsa, Alejandro

February 2019

Background: The aim of our study was to investigate the influence of conventional synthetic disease-...

Additional file 3: of A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable

Alessio Cortellini (6409283)
Melissa Bersanelli (3797482)
Sebastiano Buti (3797485)
Katia Cannita (6409292)
Daniele Santini (222870)
Fabiana Perrone (6409298)
Raffaele Giusti (6409304)
Marcello Tiseo (475209)
Maria Michiara (62208)
Pietro Di Marino (6409310)
Nicola Tinari (350375)
Michele De Tursi (548921)
Federica Zoratto (6409313)
Enzo Veltri (6409316)
Riccardo Marconcini (6409319)
Francesco Malorgio (6409322)
Marco Russano (3148566)
Cecilia Anesi (6409325)
Tea Zeppola (6409328)
Marco Filetti (276152)
Paolo Marchetti (393307)
Andrea Botticelli (3133263)
Gian Antonini Cappellini (6409334)
Federica De Galitiis (6409337)
Maria Vitale (3528125)
Francesca Rastelli (6409340)
Federica Pergolesi (6409343)
Rossana Berardi (477376)
Silvia Rinaldi (2054881)
Marianna Tudini (6409346)
Rosa Silva (485080)
Annagrazia Pireddu (6409349)
Francesco Atzori (4745331)
Rita Chiari (6409352)
Biagio Ricciuti (6409355)
Andrea De Giglio (6409358)
Daniela Iacono (6409361)
Alain Gelibter (6409364)
Mario Occhipinti (3133260)
Alessandro Parisi (6409367)
Giampiero Porzio (6409370)
Maria Fargnoli (6116600)
Paolo Ascierto (3777298)
Corrado Ficorella (6409373)
Clara Natoli (548918)

February 2019

Univariate and multivariate analyses with logistic regression of Objective Response Rate. (DOC 49 kb

Additional file 2: of A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable

Alessio Cortellini (6409283)
Melissa Bersanelli (3797482)
Sebastiano Buti (3797485)
Katia Cannita (6409292)
Daniele Santini (222870)
Fabiana Perrone (6409298)
Raffaele Giusti (6409304)
Marcello Tiseo (475209)
Maria Michiara (62208)
Pietro Di Marino (6409310)
Nicola Tinari (350375)
Michele De Tursi (548921)
Federica Zoratto (6409313)
Enzo Veltri (6409316)
Riccardo Marconcini (6409319)
Francesco Malorgio (6409322)
Marco Russano (3148566)
Cecilia Anesi (6409325)
Tea Zeppola (6409328)
Marco Filetti (276152)
Paolo Marchetti (393307)
Andrea Botticelli (3133263)
Gian Antonini Cappellini (6409334)
Federica De Galitiis (6409337)
Maria Vitale (3528125)
Francesca Rastelli (6409340)
Federica Pergolesi (6409343)
Rossana Berardi (477376)
Silvia Rinaldi (2054881)
Marianna Tudini (6409346)
Rosa Silva (485080)
Annagrazia Pireddu (6409349)
Francesco Atzori (4745331)
Rita Chiari (6409352)
Biagio Ricciuti (6409355)
Andrea De Giglio (6409358)
Daniela Iacono (6409361)
Alain Gelibter (6409364)
Mario Occhipinti (3133260)
Alessandro Parisi (6409367)
Giampiero Porzio (6409370)
Maria Fargnoli (6116600)
Paolo Ascierto (3777298)
Corrado Ficorella (6409373)
Clara Natoli (548918)

February 2019

Immune-related adverse events of any grade and G3/G4 immune-related adverse events. (DOCX 15 kb

Additional file 1: of Association of Metabolic Markers with self-reported osteoarthritis among middle-aged BMI-defined non-obese individuals: a cross-sectional study

Kelsey Collins (5710076)
Behnam Sharif (338153)
Raylene Reimer (3416024)
Claudia Sanmartin (549893)
Walter Herzog (713967)
Rick Chin (352186)
Deborah Marshall (3415802)

September 2018

BMI and body fat percentage classification. The supplementary data provides a summary of the sample ...

Additional file 4: of Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons

Lukas Mangnus (3496604)
Wouter Nieuwenhuis (3496595)
Hanna van Steenbergen (3496592)
Tom Huizinga (3398660)
Monique Reijnierse (3496598)
Annette van der Helm-van Mil (3496601)

October 2016

is a figure showing correlations of BMI with MRI-detected inflammation in inflammatory osteoarthriti...

Dana Friedrich (4642099)
Hanns-Ulrich Marschall (506679)
Frank Lammert (2875)

June 2018

Table S1. Prevalence of comorbidities in overweight (Nâ=â14) and obese (12) NAFLD patients. In o...

Additional file 2: of Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons

Lukas Mangnus (3496604)
Wouter Nieuwenhuis (3496595)
Hanna van Steenbergen (3496592)
Tom Huizinga (3398660)
Monique Reijnierse (3496598)
Annette van der Helm-van Mil (3496601)

October 2016

is a table presenting the ICC for total inflammation score for 30 arthritis patients scored by all f...

Additional file 1: of Exploring the associations between systemic inflammation, obesity and healthy days: a health related quality of life (HRQOL) analysis of NHANES 2005–2008

Jeffrey Wilkins (5596064)
Palash Ghosh (5596067)
Juan Vivar (599734)
Bibhas Chakraborty (5596070)
Sujoy Ghosh (51427)

August 2018

Exploring the associations between systemic inflammation, obesity and healthy days: a health related...

Leslie Harrold (2578624)
Heather Litman (3967853)
Katherine Saunders (3967850)
Kimberly Dandreo (4763781)
Bernice Gershenson (4763790)
Jeffrey Greenberg (3502604)
Robert Low (4763784)
Jeffrey Stark (4763793)
Robert Suruki (443240)
Srihari Jaganathan (4763787)
Joel Kremer (3475457)
Mohamed Yassine (4763778)

January 2018

Modified Charlson comorbidity index. Table S1. Other AEs of interest. (PDF 246Â kb

Additional file 2: of Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patientsâimmune-related candidate proteins affected by TNF blocking treatment

Johanna Estelius (4846906)
Johan Lengqvist (555763)
Elena Ossipova (666249)
Helena Idborg (2579896)
Erwan MaĂŽtre (6370364)
Magnus Andersson (236322)
Lou Brundin (221842)
Mohsen Khademi (221840)
Elisabet Svenungsson (70507)
Per-Johan Jakobsson (356891)
Jon Lampa (54464)

February 2019

Figure S1. PLS-DA was performed on proteomic data. Figure S2. Overlap between proteins detected in C...

Additional file 2: Figure S2. of Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis

Raphael Micheroli (4260031)
Monika Hebeisen (4260037)
Lukas Wildi (4260040)
Pascale Exer (3543695)
Giorgio Tamborrini (3543689)
JĂźrg Bernhard (3543698)
Burkhard MĂśller (4260046)
Pascal Zufferey (4260034)
Michael Nissen (4260043)
Almut Scherer (20370)
Adrian Ciurea (763222)

July 2017

Body height before and after correction for kyphosis by using the occiput-to-wall distance. (DOC 118...

Additional file 1: of Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation

Jiahua Fan (6249098)
Yangqing Liu (289844)
Songping Yin (6249101)
Nixuan Chen (6249104)
Xinxiu Bai (6249110)
Qiuyi Ke (6249113)
Jia Shen (1828945)
Min Xia (307622)

January 2019

Figure S1. The relationship between sdLDL-c/LDL-c ratio and prevalence of MetS. Table S1. Logistic r...

Additional file 1: of Patient-reported outcomes from a randomized phase III trial of sarilumab monotherapy versus adalimumab monotherapy in patients with rheumatoid arthritis

Vibeke Strand (410780)
Laure Gossec (4058521)
Clare Proudfoot (5165081)
Chieh-I Chen (4415830)
Matthew Reaney (5424773)
Sophie Guillonneau (5424776)
Toshio Kimura (5424779)
Janet van Adelsberg (5424782)
Yong Lin (177139)
Erin Mangan (5424785)
Hubert van Hoogstraten (5079860)
Gerd Burmester (52016)

June 2018

Table S1. LSM changes in RAID individual domain scores from baseline to week 24 with sarilumab 200Â ...

Additional file 1: of Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis

Abstract

Extracted data

Additional file 1: of Association between concomitant csDMARDs and clinical response to TNF inhibitors in overweight patients with axial spondyloarthritis

Abstract

Extracted data

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