Additional file 1: of Glial activation and inflammation along the Alzheimer’s disease continuum

Additional file 1: of Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study

Kimberly Willik (6530522)
Lana Fani (6293855)
Dimitris Rizopoulos (677667)
Silvan Licher (6293843)
Jesse Fest (6530525)
Sanne Schagen (3760576)
M. Ikram (3475238)

March 2019

Table S1. Overview of median blood cell counts and blood cell-based ratios measured per Rotterdam St...

Additional file 3: of The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimerâs pathology

Sarah Westwood (3950540)
Benjamine Liu (3950531)
Alison Baird (3950534)
Sneha Anand (3950525)
Alejo Nevado-Holgado (3950537)
Danielle Newby (1695076)
Maria Pikkarainen (3950528)
Merja Hallikainen (342085)
Johanna Kuusisto (197767)
Johannes Streffer (328683)
Gerald Novak (791919)
Kaj Blennow (58615)
Ulf Andreasson (185596)
Henrik Zetterberg (144718)
Ulf Smith (258969)
Markku Laakso (197777)
Hilkka Soininen (120808)
Simon Lovestone (84515)

April 2017

Table presenting correlation results of CSF SOMAscan proteins with CSF markers of AD pathology (CSV ...

Additional file 1: of Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia

Pooja-Shree Mishra (3501329)
K. Vijayalakshmi (2015191)
A. Nalini (3501335)
T. Sathyaprabha (3501323)
B. Kramer (4690003)
Phalguni Alladi (3501326)
T. Raju (556903)

December 2017

Details of the CSF samples taken for the study. Table S1 describes the age and gender of the subject...

Additional file 3: of Glial activation and inflammation along the Alzheimer’s disease continuum

Kaja Nordengen (6389465)
Bjørn-Eivind Kirsebom (6389471)
Kristi Henjum (2795560)
Per Selnes (3527429)
Berglind Gísladóttir (6389477)
Marianne Wettergreen (1491346)
Silje Torsetnes (6389480)
Gøril Grøntvedt (3513869)
Knut Waterloo (6389483)
Dag Aarsland (157629)
Lars Nilsson (330562)
Tormod Fladby (706325)

February 2019

Figure S2. Between-group comparisons of microglial- and astroglial activation with inflammation base...

Additional file 1: of Systemic infection modifies the neuroinflammatory response in late stage Alzheimer’s disease

Sonja Rakic (5729885)
Yat Hung (5729888)
Matthew Smith (326340)
Denise So (5729891)
Hannah Tayler (5729894)
William Varney (5729897)
Joe Wild (5729900)
Scott Harris (306518)
Clive Holmes (237359)
Seth Love (122101)
William Stewart (28871)
James Nicoll (4733223)
Delphine Boche (458992)

September 2018

Table S1. Characteristics of the primary antibodies, immunohistochemistry conditions and expression ...

Additional file 1: of Circulating levels of IL-1 family cytokines and receptors in Alzheimer’s disease: new markers of disease progression?

Paola Italiani (519267)
Ilaria Puxeddu (303574)
Sabrina Napoletano (6081056)
Emanuele Scala (6081059)
Daniela Melillo (545973)
Simone Manocchio (6081062)
Antonella Angiolillo (2795587)
Paola Migliorini (361490)
Diana Boraschi (5088)
Emilia Vitale (271466)
Alfonso Costanzo (6081065)

December 2018

Results of multiple linear regression models without control for confounding variables. Values are β...

Additional file 6: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimerâs disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S6. Top AD risk genes in Blue, Magenta and Yellow AD-associated microglial modules. (XLSX 22Â ...

Additional file 2: of Circulating levels of IL-1 family cytokines and receptors in Alzheimer’s disease: new markers of disease progression?

Paola Italiani (519267)
Ilaria Puxeddu (303574)
Sabrina Napoletano (6081056)
Emanuele Scala (6081059)
Daniela Melillo (545973)
Simone Manocchio (6081062)
Antonella Angiolillo (2795587)
Paola Migliorini (361490)
Diana Boraschi (5088)
Emilia Vitale (271466)
Alfonso Costanzo (6081065)

December 2018

Results of multiple linear regression models with control for confounding variables. Values are β co...

Additional file 5: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S5. Enrichment analysis of GWAS-identified human AD-risk genes in mouse microglial modules. (X...

Additional file 1: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimerâs disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S1. Mouse microglial transcriptomic modules identified by Weighted Correlation Network Analysi...

Additional file 1: of Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimerâs disease-related proteins

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Ali Raza (4905754)
Tianwen Gao (262800)
Hailian Xiao (36120)
Ranjita Betarbet (4174207)
Duc Duong (4174198)
James Webster (3633883)
Chadwick Hales (3491627)
James Lah (3504050)
Allan Levey (3504062)
Nicholas Seyfried (3504065)

June 2018

Table S1. Log2 transformed protein abundance data and differential expression analyses. (XLSX 1522 k...

Additional file 1: of Genetic risk for Alzheimerâs disease is concentrated in specific macrophage and microglial transcriptional networks

Katherine Tansey (4889533)
Darren Cameron (4889530)
Matthew Hill (394308)

February 2018

Table S1. Enrichment of AD-risk variants at DHSs from Roadmap Epigenomics Consortium data. (XLSX 36 ...

Additional file 1: of Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimerâs disease

Qi Zhang (28502)
Cheng Ma (298689)
Marla Gearing (1939525)
Peng Wang (34436)
Lih-Shen Chin (62183)
Lian Li (49049)

March 2018

Table S1. Demographic and neuropathological data of human AD patient and control cases. For each cas...

Additional file 3: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S3. Identification of potential transcriptional regulators of mouse microglial modules. (XLSX ...

Additional file 1: of Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimerâs disease

Minghui Wang (15418)
Panos Roussos (318249)
Andrew McKenzie (522240)
Xianxiao Zhou (3464498)
Yuji Kajiwara (265261)
Kristen Brennand (228552)
Gabriele De Luca (244081)
John Crary (3464492)
Patrizia Casaccia (225204)
Joseph Buxbaum (3464495)
Michelle Ehrlich (3453359)
Sam Gandy (6210)
Alison Goate (48756)
Pavel Katsel (257692)
Eric Schadt (105785)
Vahram Haroutunian (23823)
Bin Zhang (64682)

November 2016

This document contains Supplementary Tables S1â16, plus their associated legends/captions. (XLSX 6...

Additional file 1: of Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study

Kimberly Willik (6530522)
Lana Fani (6293855)
Dimitris Rizopoulos (677667)
Silvan Licher (6293843)
Jesse Fest (6530525)
Sanne Schagen (3760576)
M. Ikram (3475238)

March 2019

Table S1. Overview of median blood cell counts and blood cell-based ratios measured per Rotterdam St...

Additional file 3: of The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimerâs pathology

Sarah Westwood (3950540)
Benjamine Liu (3950531)
Alison Baird (3950534)
Sneha Anand (3950525)
Alejo Nevado-Holgado (3950537)
Danielle Newby (1695076)
Maria Pikkarainen (3950528)
Merja Hallikainen (342085)
Johanna Kuusisto (197767)
Johannes Streffer (328683)
Gerald Novak (791919)
Kaj Blennow (58615)
Ulf Andreasson (185596)
Henrik Zetterberg (144718)
Ulf Smith (258969)
Markku Laakso (197777)
Hilkka Soininen (120808)
Simon Lovestone (84515)

April 2017

Table presenting correlation results of CSF SOMAscan proteins with CSF markers of AD pathology (CSV ...

Additional file 1: of Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia

Pooja-Shree Mishra (3501329)
K. Vijayalakshmi (2015191)
A. Nalini (3501335)
T. Sathyaprabha (3501323)
B. Kramer (4690003)
Phalguni Alladi (3501326)
T. Raju (556903)

December 2017

Details of the CSF samples taken for the study. Table S1 describes the age and gender of the subject...

Additional file 3: of Glial activation and inflammation along the Alzheimer’s disease continuum

Kaja Nordengen (6389465)
Bjørn-Eivind Kirsebom (6389471)
Kristi Henjum (2795560)
Per Selnes (3527429)
Berglind Gísladóttir (6389477)
Marianne Wettergreen (1491346)
Silje Torsetnes (6389480)
Gøril Grøntvedt (3513869)
Knut Waterloo (6389483)
Dag Aarsland (157629)
Lars Nilsson (330562)
Tormod Fladby (706325)

February 2019

Figure S2. Between-group comparisons of microglial- and astroglial activation with inflammation base...

Additional file 1: of Systemic infection modifies the neuroinflammatory response in late stage Alzheimer’s disease

Sonja Rakic (5729885)
Yat Hung (5729888)
Matthew Smith (326340)
Denise So (5729891)
Hannah Tayler (5729894)
William Varney (5729897)
Joe Wild (5729900)
Scott Harris (306518)
Clive Holmes (237359)
Seth Love (122101)
William Stewart (28871)
James Nicoll (4733223)
Delphine Boche (458992)

September 2018

Table S1. Characteristics of the primary antibodies, immunohistochemistry conditions and expression ...

Additional file 1: of Circulating levels of IL-1 family cytokines and receptors in Alzheimer’s disease: new markers of disease progression?

Paola Italiani (519267)
Ilaria Puxeddu (303574)
Sabrina Napoletano (6081056)
Emanuele Scala (6081059)
Daniela Melillo (545973)
Simone Manocchio (6081062)
Antonella Angiolillo (2795587)
Paola Migliorini (361490)
Diana Boraschi (5088)
Emilia Vitale (271466)
Alfonso Costanzo (6081065)

December 2018

Results of multiple linear regression models without control for confounding variables. Values are β...

Additional file 6: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimerâs disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S6. Top AD risk genes in Blue, Magenta and Yellow AD-associated microglial modules. (XLSX 22Â ...

Additional file 2: of Circulating levels of IL-1 family cytokines and receptors in Alzheimer’s disease: new markers of disease progression?

Paola Italiani (519267)
Ilaria Puxeddu (303574)
Sabrina Napoletano (6081056)
Emanuele Scala (6081059)
Daniela Melillo (545973)
Simone Manocchio (6081062)
Antonella Angiolillo (2795587)
Paola Migliorini (361490)
Diana Boraschi (5088)
Emilia Vitale (271466)
Alfonso Costanzo (6081065)

December 2018

Results of multiple linear regression models with control for confounding variables. Values are β co...

Additional file 5: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S5. Enrichment analysis of GWAS-identified human AD-risk genes in mouse microglial modules. (X...

Additional file 1: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimerâs disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S1. Mouse microglial transcriptomic modules identified by Weighted Correlation Network Analysi...

Additional file 1: of Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimerâs disease-related proteins

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Ali Raza (4905754)
Tianwen Gao (262800)
Hailian Xiao (36120)
Ranjita Betarbet (4174207)
Duc Duong (4174198)
James Webster (3633883)
Chadwick Hales (3491627)
James Lah (3504050)
Allan Levey (3504062)
Nicholas Seyfried (3504065)

June 2018

Table S1. Log2 transformed protein abundance data and differential expression analyses. (XLSX 1522 k...

Additional file 1: of Genetic risk for Alzheimerâs disease is concentrated in specific macrophage and microglial transcriptional networks

Katherine Tansey (4889533)
Darren Cameron (4889530)
Matthew Hill (394308)

February 2018

Table S1. Enrichment of AD-risk variants at DHSs from Roadmap Epigenomics Consortium data. (XLSX 36 ...

Additional file 1: of Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimerâs disease

Qi Zhang (28502)
Cheng Ma (298689)
Marla Gearing (1939525)
Peng Wang (34436)
Lih-Shen Chin (62183)
Lian Li (49049)

March 2018

Table S1. Demographic and neuropathological data of human AD patient and control cases. For each cas...

Additional file 3: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

Srikant Rangaraju (4174204)
Eric Dammer (4174213)
Syed Raza (4174210)
Priyadharshini Rathakrishnan (5245535)
Hailian Xiao (36120)
Tianwen Gao (262800)
Duc Duong (4174198)
Michael Pennington (1343655)
James Lah (3504050)
Nicholas Seyfried (3504065)
Allan Levey (3504062)

May 2018

Table S3. Identification of potential transcriptional regulators of mouse microglial modules. (XLSX ...

Additional file 1: of Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimerâs disease

Minghui Wang (15418)
Panos Roussos (318249)
Andrew McKenzie (522240)
Xianxiao Zhou (3464498)
Yuji Kajiwara (265261)
Kristen Brennand (228552)
Gabriele De Luca (244081)
John Crary (3464492)
Patrizia Casaccia (225204)
Joseph Buxbaum (3464495)
Michelle Ehrlich (3453359)
Sam Gandy (6210)
Alison Goate (48756)
Pavel Katsel (257692)
Eric Schadt (105785)
Vahram Haroutunian (23823)
Bin Zhang (64682)

November 2016

This document contains Supplementary Tables S1â16, plus their associated legends/captions. (XLSX 6...

Additional file 1: of Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study

Kimberly Willik (6530522)
Lana Fani (6293855)
Dimitris Rizopoulos (677667)
Silvan Licher (6293843)
Jesse Fest (6530525)
Sanne Schagen (3760576)
M. Ikram (3475238)

March 2019

Table S1. Overview of median blood cell counts and blood cell-based ratios measured per Rotterdam St...

Additional file 3: of The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimerâs pathology

Sarah Westwood (3950540)
Benjamine Liu (3950531)
Alison Baird (3950534)
Sneha Anand (3950525)
Alejo Nevado-Holgado (3950537)
Danielle Newby (1695076)
Maria Pikkarainen (3950528)
Merja Hallikainen (342085)
Johanna Kuusisto (197767)
Johannes Streffer (328683)
Gerald Novak (791919)
Kaj Blennow (58615)
Ulf Andreasson (185596)
Henrik Zetterberg (144718)
Ulf Smith (258969)
Markku Laakso (197777)
Hilkka Soininen (120808)
Simon Lovestone (84515)

April 2017

Table presenting correlation results of CSF SOMAscan proteins with CSF markers of AD pathology (CSV ...

Additional file 1: of Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia

Pooja-Shree Mishra (3501329)
K. Vijayalakshmi (2015191)
A. Nalini (3501335)
T. Sathyaprabha (3501323)
B. Kramer (4690003)
Phalguni Alladi (3501326)
T. Raju (556903)

December 2017

Details of the CSF samples taken for the study. Table S1 describes the age and gender of the subject...

Additional file 1: of Glial activation and inflammation along the Alzheimer’s disease continuum

Abstract

Extracted data

Additional file 1: of Glial activation and inflammation along the Alzheimer’s disease continuum

Abstract

Extracted data

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