Numerical evaluation of clinical signs (NECS).

Clinical signs were evaluated 150, 180, 240, and 300 dpi. GI: dogs which received two doses of 200μg pPAL-LACK + 20μg pPAL-canIL12-p35 + 20μg pPAL-canIL12-p40. GII: infection control group. Represented values are the sum of 0–5 scores provided to each of the clinical signs observed. Positive standard deviations have been represented. *Several dogs had to be euthanized before the end of the experiment (after the 240dpi time point) for ethical reasons.