Expression of GAL4DBD-Prdm12b constructs used in transfection experiments. a. Immunoblot showing expression of GAL4DBD-Prdm12b constructs in transfected HEK293T cells. All constructs are stable except Myc-GAL4-∆PR-prdm12b. b. Immunoblot showing expression of Myc-Flag-G9a and Myc-Flag-Bhlhe22 constructs in transfected HEK 293 T cells. (PDF 619 kb
The bacterial artificial chromosome (BAC) reporter line Tg(nkx6.1:eGFP) mirrors the expression of th...
Abstract Background Functioning of the adult nervous system depends on the establishment of neural c...
Notch-responsive terminal end duct cells/CACs give rise to other ductal cells. Immunodetection of H2...
Characterization of the prdm12bsa9887 mutant. a. Schematic showing genomic sequence of prdm12b. Exon...
Sequence of mutant prdm12b, bhlhe22 and nkx6.1 alleles. The predicted amino acid sequence for each m...
Sequences of primers used to genotype mutant lines. Detailed features of primers used to genotype mu...
Generation of bhlhe22 germline mutant. a. Schematic showing genomic sequence of bhlhe22 with the bHL...
Generation of germ line nkx6.1 mutants. a. Schematic showing genomic sequence of nkx6.1 with the hom...
Detailed analysis of the touch-evoked escape response in prdm12b mutant and wild type animals. a, b....
Movie of prdm12b mutant touch-evoked escape response. Movie of representative prdm12b mutant animal ...
Movie of prdm12b mutant touch-evoked escape response. The same prdm12b mutant animal as in Additiona...
Movie of prdm12b mutant touch-evoked escape response. Movie of representative prdm12b mutant animal ...
Movie of wild type touch-evoked response. Movie of representative wild type animal tapped on the hea...
ascl1b expression is not repressed by Nkx6.1. A Schematic representation of wild-type (WT) and mutan...
Figure S7. Scheme for generating gbx1 mutant line. (A) Schematic showing the 20 nucleotide (orange t...
The bacterial artificial chromosome (BAC) reporter line Tg(nkx6.1:eGFP) mirrors the expression of th...
Abstract Background Functioning of the adult nervous system depends on the establishment of neural c...
Notch-responsive terminal end duct cells/CACs give rise to other ductal cells. Immunodetection of H2...
Characterization of the prdm12bsa9887 mutant. a. Schematic showing genomic sequence of prdm12b. Exon...
Sequence of mutant prdm12b, bhlhe22 and nkx6.1 alleles. The predicted amino acid sequence for each m...
Sequences of primers used to genotype mutant lines. Detailed features of primers used to genotype mu...
Generation of bhlhe22 germline mutant. a. Schematic showing genomic sequence of bhlhe22 with the bHL...
Generation of germ line nkx6.1 mutants. a. Schematic showing genomic sequence of nkx6.1 with the hom...
Detailed analysis of the touch-evoked escape response in prdm12b mutant and wild type animals. a, b....
Movie of prdm12b mutant touch-evoked escape response. Movie of representative prdm12b mutant animal ...
Movie of prdm12b mutant touch-evoked escape response. The same prdm12b mutant animal as in Additiona...
Movie of prdm12b mutant touch-evoked escape response. Movie of representative prdm12b mutant animal ...
Movie of wild type touch-evoked response. Movie of representative wild type animal tapped on the hea...
ascl1b expression is not repressed by Nkx6.1. A Schematic representation of wild-type (WT) and mutan...
Figure S7. Scheme for generating gbx1 mutant line. (A) Schematic showing the 20 nucleotide (orange t...
The bacterial artificial chromosome (BAC) reporter line Tg(nkx6.1:eGFP) mirrors the expression of th...
Abstract Background Functioning of the adult nervous system depends on the establishment of neural c...
Notch-responsive terminal end duct cells/CACs give rise to other ductal cells. Immunodetection of H2...