Steady state concentrations of selected metabolites as functions of ξ, for the simulations of the CHO-K1 metabolic network. Representative values of β are plotted (see legend). The purple line corresponds to the β → ∞ limit. To reduce clutter, this figure does not distinguish between stable and unstable steady states.</p
<p>All simulations were performed using mathematical model 1 with standard parameters listed in <a h...
Schematics of exposure patterns are shown in gray scale, qualitatively indicating high or low steady...
<p>Percentage Increase in Steady State Metabolite Concentrations, from the Keio Phenotype to the Alt...
The different panels show the steady state values of (a) D, (b) X, (c) sg and (d) sw, as functions o...
<p>Plots along left illustrate the convergence of the model metabolite concentrations (solid lines) ...
Dilution rate (a) and cell density (b) as functions of ξ. (c) Cell density versus dilution rate. Dif...
<p>* No lower bounds were imposed on H<sub>2</sub> or formate concentrations, which can fall below 0...
<p>This plot of the trajectories of 4 kinetic model metabolite concentrations over time shows that s...
Plot of the steady state cell density as a multi-function of the dilution rate, for different values...
textabstractThe steady-state assumption, which states that the production and consumption of metabol...
<p>Using the metabolic model of CHO-K1 and the media IMDM, we plot metabolite uptakes (black, left-a...
<p>Panels A and C: Steady-state flux through the FA β-oxidation. Panel B: CoASH concentration (solid...
AbstractThe steady-state assumption, which states that the production and consumption of metabolites...
<p>The contour lines indicate when steady-state was reached (in minutes of simulated time). If stead...
<p>The network consists of seven metabolites and seven irreversible reactions. We assume that metabo...
<p>All simulations were performed using mathematical model 1 with standard parameters listed in <a h...
Schematics of exposure patterns are shown in gray scale, qualitatively indicating high or low steady...
<p>Percentage Increase in Steady State Metabolite Concentrations, from the Keio Phenotype to the Alt...
The different panels show the steady state values of (a) D, (b) X, (c) sg and (d) sw, as functions o...
<p>Plots along left illustrate the convergence of the model metabolite concentrations (solid lines) ...
Dilution rate (a) and cell density (b) as functions of ξ. (c) Cell density versus dilution rate. Dif...
<p>* No lower bounds were imposed on H<sub>2</sub> or formate concentrations, which can fall below 0...
<p>This plot of the trajectories of 4 kinetic model metabolite concentrations over time shows that s...
Plot of the steady state cell density as a multi-function of the dilution rate, for different values...
textabstractThe steady-state assumption, which states that the production and consumption of metabol...
<p>Using the metabolic model of CHO-K1 and the media IMDM, we plot metabolite uptakes (black, left-a...
<p>Panels A and C: Steady-state flux through the FA β-oxidation. Panel B: CoASH concentration (solid...
AbstractThe steady-state assumption, which states that the production and consumption of metabolites...
<p>The contour lines indicate when steady-state was reached (in minutes of simulated time). If stead...
<p>The network consists of seven metabolites and seven irreversible reactions. We assume that metabo...
<p>All simulations were performed using mathematical model 1 with standard parameters listed in <a h...
Schematics of exposure patterns are shown in gray scale, qualitatively indicating high or low steady...
<p>Percentage Increase in Steady State Metabolite Concentrations, from the Keio Phenotype to the Alt...