The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fatty-acid regulation, and detoxify ammonia—is susceptible to injuries induced by drugs and toxic substances. Although plasma metabolite profiles are increasingly investigated for their potential to detect liver injury earlier than current clinical markers, their utility may be compromised because such profiles are affected by the nutritional state and the physiological state of the animal, and by contributions from extrahepatic sources. To tease apart the contributions of liver and non-liver sources to alterations in plasma metabolite profiles, here we sought to computationally isolate the plasma metabolite changes originating in the liver dur...
An in silico liver was developed in attempt to represent the in vivo state of the fasted liver. It f...
Context-specific Genome-scale Metabolic Network Reconstructions (GENREs) provide a means to understa...
Being the central metabolic organ of vertebrates, the liver possesses the largest repertoire of meta...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
Mapping network analysis in cells and tissues can provide insights into metabolic adaptations to cha...
Communication Posters Session AlimentationCommunication PostersSession AlimentationPhenotypic altera...
A metabolomic approach was applied to a mouse model of starvation-induced hepatic steatosis. After 2...
An in silico liver was developed in attempt to represent the in vivo state of the fasted liver. It f...
Context-specific Genome-scale Metabolic Network Reconstructions (GENREs) provide a means to understa...
Being the central metabolic organ of vertebrates, the liver possesses the largest repertoire of meta...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
The liver—a central metabolic organ that integrates whole-body metabolism to maintain glucose and fa...
Mapping network analysis in cells and tissues can provide insights into metabolic adaptations to cha...
Communication Posters Session AlimentationCommunication PostersSession AlimentationPhenotypic altera...
A metabolomic approach was applied to a mouse model of starvation-induced hepatic steatosis. After 2...
An in silico liver was developed in attempt to represent the in vivo state of the fasted liver. It f...
Context-specific Genome-scale Metabolic Network Reconstructions (GENREs) provide a means to understa...
Being the central metabolic organ of vertebrates, the liver possesses the largest repertoire of meta...