Development of macroscopic cartilage damage following ACL transection.

Total cartilage lesion area at 6 and 12 months after untreated ACL injury (ACLT) and bridge-enhanced ACL repair (BEAR). Data is presented as Mean ± SD. P value is derived from a one-way ANOVA with posthoc Bonferroni correction for multiple comparisons (adopted and modified with permission from Murray MM and Fleming BC, Am J Sports Med 2013 [12]) Macroscopic cartilage damage was assessed by measuring the cartilage lesions across the femoral condyles and tibial plateau in medial and lateral compartments using India ink staining and calipers [12].