Additional file 2: of Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy

Kaplan-Meier survival analysis of mice groups made of pooled MSC-Vcz treatments: 1) in one group we combined treatments with all tested 5-FIC concentrations (20, 50 and 100 mg/mouse), 2) the second group contained treatments with all tested 5-FU concentrations (20 and 50 mg/mouse) and 3) the third treatment group was composed of MSC-Vcz controls. The asterisk symbol (*) marks the statistical significance between MSC-Vcz + 5-FIC and control treatment groups, determined by the p-value = 0.01 of the Chi-square test. The Log rank value for 5-FIC vs control groups was determined as p < 0.001 (significant), whereas the Log rank value for 5-FU vs control groups was determined as p = 0.098 (not significant). (PDF 296 kb