MS-275 and RGFP966 did not reduce oxidases and restore antioxidant enzymes in angiotensin (Ang) II-induced hypertensive mice.
- Yuhee Ryu (3370769)
- Hae Jin Kee (824000)
- Simei Sun (6421346)
- Young Mi Seok (6421349)
- Sin Young Choi (3370778)
- Gwi Ran Kim (3370784)
- Seung-Jung Kee (824001)
- Marc Pflieger (6421352)
- Thomas Kurz (1648405)
- Hyung-Seok Kim (1640446)
- Myung Ho Jeong (462583)
Publication date
March 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
The transcript levels of Nox1 (A), Nox2 (B), Nox4 (C), p22phox (D), p47phox (E), Cox-2 (F), and SOD3 (G) were determined using qRT-PCR in aortas of sham and Ang II-induced mice treated with vehicle, MS-275, or RGFP966. Results are ± SE (n = 8 per group). * p < 0.05 and ** p < 0.01 versus sham group; NS, not significant.</p
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