Additional file 5: of Herd immunity alters the conditions for performing dose schedule comparisons: an individual-based model of pneumococcal carriage

Figure S4. Power vs. Trial Arm Size in a Simulated Trial of Goldblatt et al. PCV13. Simulated under assumptions of less divergence between the efficacies of different dose schedules. Sample sizes for a 3 + 1 vs 2 + 1 trial are not calculated because doing so would be incoherent; the arms are essentially identical, which implies an infinite theoretical sample size. (JPG 225 kb