The equilibrium results of simulations performed in 3D and 2D both in a Voronoi lattice (i and iii) and in a regular lattice (ii and iv) are plotted with the variables being the speed of virus replication (λ) and infected cell death (δ). The mean field solution (v) is also presented for comparison. (vi) represents the mean field solution over a wider range of parameters). Red (A) represents tumor eradication, Blue (B) represents the equilibrium with the virus and normal cell elimination and green (C) represents the co-existence of all three populations.</p
In the present paper, we address by means of mathematical modeling the following main question: How ...
Oncolytic virotherapy is a promising form of cancer treatment that uses native or genetically engine...
In the graphs of the main text (Fig 3), the rate of virus spread (bi) ranges from 0 to 5, while the ...
Snapshots of the spread of an oncolytic virus in a 2D environment with a regular lattice architectur...
Oncolytic viruses are viruses that specifically infect cancer cells and kill them, while leaving hea...
Serial snapshots of the spread of an oncolytic virus in a 3D environment with a regular lattice arch...
Oncolytic viruses are viruses that specifically infect cancer cells and kill them, while leaving hea...
(A) Therapeutic outcomes in the 2D Voronoi model in relation to the rates of viral spread via contac...
(A) Therapeutic outcomes in the 2D Voronoi model in relation to the rates of viral spread via contac...
In our model, virus infection in the tumour tissue can result in four therapeutic outcomes: (A) tota...
(A) Effect of the probability of becoming resistant (Cr) and the degree of resistance (Rr) on the th...
For three scenarios: (A) absence of virus-resistant cancer cells; (B) production of resistant cancer...
Oncolytic virotherapy is a promising form of cancer treatment that uses native or genetically engine...
One of the most promising strategies to treat cancer is attacking it with viruses. Oncolytic viruses...
A snapshot of the (A) Voronoi model and the (B) 3D model at a runtime (t = 155) was taken for compar...
In the present paper, we address by means of mathematical modeling the following main question: How ...
Oncolytic virotherapy is a promising form of cancer treatment that uses native or genetically engine...
In the graphs of the main text (Fig 3), the rate of virus spread (bi) ranges from 0 to 5, while the ...
Snapshots of the spread of an oncolytic virus in a 2D environment with a regular lattice architectur...
Oncolytic viruses are viruses that specifically infect cancer cells and kill them, while leaving hea...
Serial snapshots of the spread of an oncolytic virus in a 3D environment with a regular lattice arch...
Oncolytic viruses are viruses that specifically infect cancer cells and kill them, while leaving hea...
(A) Therapeutic outcomes in the 2D Voronoi model in relation to the rates of viral spread via contac...
(A) Therapeutic outcomes in the 2D Voronoi model in relation to the rates of viral spread via contac...
In our model, virus infection in the tumour tissue can result in four therapeutic outcomes: (A) tota...
(A) Effect of the probability of becoming resistant (Cr) and the degree of resistance (Rr) on the th...
For three scenarios: (A) absence of virus-resistant cancer cells; (B) production of resistant cancer...
Oncolytic virotherapy is a promising form of cancer treatment that uses native or genetically engine...
One of the most promising strategies to treat cancer is attacking it with viruses. Oncolytic viruses...
A snapshot of the (A) Voronoi model and the (B) 3D model at a runtime (t = 155) was taken for compar...
In the present paper, we address by means of mathematical modeling the following main question: How ...
Oncolytic virotherapy is a promising form of cancer treatment that uses native or genetically engine...
In the graphs of the main text (Fig 3), the rate of virus spread (bi) ranges from 0 to 5, while the ...