An agent-based model of cancer evolution.

(A) A flowchart of the simulation. In each time step, a cell divides into two daughter cells with a probability g. In each cell division, each of the two daughter cells acquires k ∼ Pois(m/2) mutations. (B) A growth rule on a one-dimensional lattice. Cell divides while pushing out neighboring cells on a one-dimensional lattice with free-ends. Resources are provided from both the ends and subject to exponential decays with a half-distance parameter d.