Four-chambered view of wild type controls (A, E and I) and mutant (B-D, F-H and J-K) Furin hearts for the different cre lines used in that study using high-resolution episcopic microscopy (HREM). Inset in C represent a left septal view of the VSD in the same image). Red arrows, VSD. White arrows, PTA. RA, right atria. LA, left atria. LV, left ventricle. RV, right ventricle, PTA, persistent truncus arteriosus. In each image is indicated: number of hearts with the phenotype/number of samples analysed.</p
<p><b>(A)</b> Z stacks from <i>in situ</i> hearts (1 week old) stained with phalloidin to show actin...
<p>(A) Hearts isolated from six wild-type (WT) and six AKAP13<sup>ΔGEF/ΔGEF</sup> (ΔGEF) adult male ...
<p>A: Representative images of Wt1 immuno-stained coronal cryo-sections of <i>EHC</i> heterozygous a...
(A, D) Sections of an adult mouse wild type (n = 3) and mutant (n = 3) hearts (11 weeks old) stained...
(A-F) Immunostaining showing the expression of pSMAD1/5 (red), cTNI (green) and TBX3 (white) in the ...
(A-F) Study of Furin expression in the E15.5 mouse heart. (A, C) Furin mRNA expression as detected b...
(A-H) Immunofluorescences of E18.5 mouse wild type (n = 2) and mutant (n = 2) hearts revealing the d...
<p>(A) Representative sections of hearts from the indicated mice stained with hematoxylin and eosin....
(A, B) Right side views of E9.5 control and Nkx2-5IRES-Cre/+/Furinfl/fl mutant embryos. (C) Measurem...
<p>(<b>A–D</b>) H&E staining of the coronal sections of the control mouse hearts at P1 showed normal...
<p>(A, B) <i>mirr</i> mutants have a reduced number of Eve clusters (arrows). (C, D) The number of O...
The heart is a specialized muscle found in all animals with a circulatory system that is responsible...
In cardiac muscle, two major filaments, actin and myosin, are organized into a specific overlapping ...
<p>H&E-stained sections of control (A–C) and <i>Alk2/Gata5-Cre</i> mutant (D–F) at three different l...
In striated muscle, the barbed ends of actin filaments are attached to Z lines. Biochemical and cell...
<p><b>(A)</b> Z stacks from <i>in situ</i> hearts (1 week old) stained with phalloidin to show actin...
<p>(A) Hearts isolated from six wild-type (WT) and six AKAP13<sup>ΔGEF/ΔGEF</sup> (ΔGEF) adult male ...
<p>A: Representative images of Wt1 immuno-stained coronal cryo-sections of <i>EHC</i> heterozygous a...
(A, D) Sections of an adult mouse wild type (n = 3) and mutant (n = 3) hearts (11 weeks old) stained...
(A-F) Immunostaining showing the expression of pSMAD1/5 (red), cTNI (green) and TBX3 (white) in the ...
(A-F) Study of Furin expression in the E15.5 mouse heart. (A, C) Furin mRNA expression as detected b...
(A-H) Immunofluorescences of E18.5 mouse wild type (n = 2) and mutant (n = 2) hearts revealing the d...
<p>(A) Representative sections of hearts from the indicated mice stained with hematoxylin and eosin....
(A, B) Right side views of E9.5 control and Nkx2-5IRES-Cre/+/Furinfl/fl mutant embryos. (C) Measurem...
<p>(<b>A–D</b>) H&E staining of the coronal sections of the control mouse hearts at P1 showed normal...
<p>(A, B) <i>mirr</i> mutants have a reduced number of Eve clusters (arrows). (C, D) The number of O...
The heart is a specialized muscle found in all animals with a circulatory system that is responsible...
In cardiac muscle, two major filaments, actin and myosin, are organized into a specific overlapping ...
<p>H&E-stained sections of control (A–C) and <i>Alk2/Gata5-Cre</i> mutant (D–F) at three different l...
In striated muscle, the barbed ends of actin filaments are attached to Z lines. Biochemical and cell...
<p><b>(A)</b> Z stacks from <i>in situ</i> hearts (1 week old) stained with phalloidin to show actin...
<p>(A) Hearts isolated from six wild-type (WT) and six AKAP13<sup>ΔGEF/ΔGEF</sup> (ΔGEF) adult male ...
<p>A: Representative images of Wt1 immuno-stained coronal cryo-sections of <i>EHC</i> heterozygous a...