Bubble charts displaying significant correlations between age, mitochondrial DNA copy number and (A) CERAD recall score [observed range 2–19, higher indicating better cognitive function] (Pearson’s corr. = 0.464, p-value = 0.001); (B) fatty acid binding protein levels (Pearson’s corr. = -0.363, p-value = 0.007) (indicated as size of bubble). Age and mtDNACN have a significant negative correlation (Pearson’s corr. = -0.288, p-value = 0.035).</p
(A) Cell-free levels appear to be higher in individuals with diabetes (t-test p-value, 0.026) and th...
Mitochondrial function has been implicated and studied in numerous complex age-related diseases. Und...
Paul Y Takahashi,1 Gregory D Jenkins,2 Benjamin P Welkie,2 Shannon K McDonnell,2 Jared M Evans,2 Jam...
Pearson’s correlations showing significant relationships between cell-free mitochondrial DNA levels ...
<p>Panels a, c, and e indicate the younger group (<10 years old) and panels b, d, and f indicate the...
Background and objectives: Previous studies suggest that lower mitochondrial DNA (mtDNA) copy number...
BACKGROUND: The identification of early markers of dementia is of increasing clinical importance. Re...
BackgroundMitochondria are the main energy source for normal neuronal functions. Mitochondrial DNA (...
Abstract Background Mitochondrial dysfunction is a feature of neurodegenerative diseases, including ...
Mitochondrial DNA (mtDNA) is present in multiple copies in human cells. We evaluated cross-sectional...
Pearson’s correlations showing significant relationships between cell-free mitochondrial DNA levels ...
The identification of biomarkers that discriminate individual ageing trajectories is a principal tar...
Identifying biological correlates of late life cognitive function is important if we are to ascertai...
Copy number of mitochondrial genomes is significantly lower in cognitively impaired individuals when...
Mitochondrial function has been implicated and studied in numerous complex age-related diseases. Und...
(A) Cell-free levels appear to be higher in individuals with diabetes (t-test p-value, 0.026) and th...
Mitochondrial function has been implicated and studied in numerous complex age-related diseases. Und...
Paul Y Takahashi,1 Gregory D Jenkins,2 Benjamin P Welkie,2 Shannon K McDonnell,2 Jared M Evans,2 Jam...
Pearson’s correlations showing significant relationships between cell-free mitochondrial DNA levels ...
<p>Panels a, c, and e indicate the younger group (<10 years old) and panels b, d, and f indicate the...
Background and objectives: Previous studies suggest that lower mitochondrial DNA (mtDNA) copy number...
BACKGROUND: The identification of early markers of dementia is of increasing clinical importance. Re...
BackgroundMitochondria are the main energy source for normal neuronal functions. Mitochondrial DNA (...
Abstract Background Mitochondrial dysfunction is a feature of neurodegenerative diseases, including ...
Mitochondrial DNA (mtDNA) is present in multiple copies in human cells. We evaluated cross-sectional...
Pearson’s correlations showing significant relationships between cell-free mitochondrial DNA levels ...
The identification of biomarkers that discriminate individual ageing trajectories is a principal tar...
Identifying biological correlates of late life cognitive function is important if we are to ascertai...
Copy number of mitochondrial genomes is significantly lower in cognitively impaired individuals when...
Mitochondrial function has been implicated and studied in numerous complex age-related diseases. Und...
(A) Cell-free levels appear to be higher in individuals with diabetes (t-test p-value, 0.026) and th...
Mitochondrial function has been implicated and studied in numerous complex age-related diseases. Und...
Paul Y Takahashi,1 Gregory D Jenkins,2 Benjamin P Welkie,2 Shannon K McDonnell,2 Jared M Evans,2 Jam...