Central peaks in cross-correlograms indicate overlap of cytoskeletal systems.

Shown are normalized average cross-correlograms between cytoskeletal systems taken from different, randomly selected cells calculated within the largest circle fitting into both cells. Therefore only artificial correlations can occur. For all correlograms: maximum set to 1.0; gray scale ranges from 0.5 (black) to 1.0 (white). Scale bars, 2 μm. In the lower row intensities along horizontal lines through the maxima are displayed. A) Actin versus microtubules, unstrained (415 cells, maximum cross-correlation 0.0517); B) actin versus microtubules, 8 h stretch (299 cells, maximum 0.0436); C) vimentin versus microtubules, unstrained (448 cells, maximum 0.0517); and D) vimentin versus microtubules, 8 h stretch (389 cells, maximum 0.0504). Note the absence of central peaks (cf. Fig 8).