Differentiated human neuroblastoma SH-SY5Y cells were transfected with expression plasmids encoding GFP-Tau3R or GFP-Tau4R. Cells expressing GFP only were used as negative controls. Immunoprecipitation (IP) was performed using GFP antibodies with and without NAP (see “Materials and Methods”). (A) Flow-through (F), first and third washes (W1 and W3) fractions were collected and analyzed by immunoblot with GFP antibody (IB: GFP). (B) Elution fractions (E) were collected and analyzed by immunoblotting (IB) with the appropriate antibodies, as listed on the figure.</p
Phosphorylation of the microtubule associated protein tau is an important modulator of its normal ph...
AbstractThe abnormal cytoskeletal organization observed in Alzheimer's disease has been suggested to...
Neurofibrillary tangles (NFTs) are a characteristic neuropathological lesion of Alzheimer's disease ...
<p>Cells transfected with either Flag-tau or Myc-14-3-3ζ or co-transfected with Flag-tau and Myc-14-...
It has been considered that tau protein is mainly a cytoplasmic protein since it is a microtubule as...
<p><b>(A)</b> Immunostaining with AT8 antibody in hESC-derived neurons transfected at 35 DIV with th...
<p>Cells transfected with either Flag-tau or Flag-tau and Myc-14-3-3ζ were fixed and then stained wi...
In Alzheimer's disease, progressive supranuclear palsy, and a number of other neurodegenerative dise...
(A) HEK293A cells were co-transfected with plasmids expressing FLAG-epitope–tagged β-catenin and PAK...
<p><b>Copyright information:</b></p><p>Taken from "Tau phosphorylation by GSK-3β promotes tangle-lik...
Rat and human fetal brain tau were probed with a panel of monoclonal antibodies (tau-1, AT8, 8D8, RT...
(A) Western blot analysis of equal amounts of protein extracts from newborn (NB) rat brain cortex an...
Tau is a microtubule-associated protein implicated in neurodegenerative tauopathies. Six tau isoform...
The clinical progression of Alzheimer disease (AD) is associated with the accumulation of tau neurof...
Tau proteins play a role in the stabilization of microtubules, but in pathological conditions, tauop...
Phosphorylation of the microtubule associated protein tau is an important modulator of its normal ph...
AbstractThe abnormal cytoskeletal organization observed in Alzheimer's disease has been suggested to...
Neurofibrillary tangles (NFTs) are a characteristic neuropathological lesion of Alzheimer's disease ...
<p>Cells transfected with either Flag-tau or Myc-14-3-3ζ or co-transfected with Flag-tau and Myc-14-...
It has been considered that tau protein is mainly a cytoplasmic protein since it is a microtubule as...
<p><b>(A)</b> Immunostaining with AT8 antibody in hESC-derived neurons transfected at 35 DIV with th...
<p>Cells transfected with either Flag-tau or Flag-tau and Myc-14-3-3ζ were fixed and then stained wi...
In Alzheimer's disease, progressive supranuclear palsy, and a number of other neurodegenerative dise...
(A) HEK293A cells were co-transfected with plasmids expressing FLAG-epitope–tagged β-catenin and PAK...
<p><b>Copyright information:</b></p><p>Taken from "Tau phosphorylation by GSK-3β promotes tangle-lik...
Rat and human fetal brain tau were probed with a panel of monoclonal antibodies (tau-1, AT8, 8D8, RT...
(A) Western blot analysis of equal amounts of protein extracts from newborn (NB) rat brain cortex an...
Tau is a microtubule-associated protein implicated in neurodegenerative tauopathies. Six tau isoform...
The clinical progression of Alzheimer disease (AD) is associated with the accumulation of tau neurof...
Tau proteins play a role in the stabilization of microtubules, but in pathological conditions, tauop...
Phosphorylation of the microtubule associated protein tau is an important modulator of its normal ph...
AbstractThe abnormal cytoskeletal organization observed in Alzheimer's disease has been suggested to...
Neurofibrillary tangles (NFTs) are a characteristic neuropathological lesion of Alzheimer's disease ...