Analysis of retinal layer thickness using OCT.

Graphs showing the mean thickness of retinal layers from OCTs of two wild-type dogs at the age of 10- and 12-years (green dots; LAB23 and LAB22, respectively) and two affected dogs at the age of 10- and 12-years (blue squares; LAB10 and LAB16, respectively). The thickness is measured every 0.5 mm from the rim of the optic nerve head (0) along the visual streak. The solid lines indicate 95% confidence intervals. Measurement of the (A) total retinal thickness, (B) inner retina (C) Rec+, (D) ONL and (E) EZ+RPE. (F) The distances presented in the five graphs are shown on the magnified OCT image from a wild-type Labrador retriever dog. OCT = optical coherence tomography; EZ = ellipsoid zone (inner-to-outer segment junction); Rec+ = total photoreceptor length; RPE = retinal pigment epithelium; ONL = outer nuclear layer.