External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort
- Marije Lamain-de Ruiter (6490886)
- Anneke Kwee (79280)
- Christiana A. Naaktgeboren (470782)
- Rebecca D. Louhanepessy (6490889)
- Inge De Groot (6490892)
- Inge M. Evers (6490895)
- Floris Groenendaal (283739)
- Yolanda R. Hering (6490898)
- Anjoke J. M. Huisjes (846639)
- Cornel Kirpestein (6490901)
- Wilma M. Monincx (6490904)
- Peter C. J. I. Schielen (224573)
- Annewil Van ’T Zelfde (6490907)
- Charlotte M. Van Oirschot (6490910)
- Simone A. Vankan-Buitelaar (6490913)
- Mariska A. A. W. Vonk (6490916)
- Therese A. Wiegers (2227117)
- Joost J. Zwart (283445)
- Karel G. M. Moons (112759)
- Arie Franx (377859)
- Maria P. H. Koster (224563)
Publication date
March 2019
DOIAbstract
Objective: To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods: Women Results: 3,736 women were included; 87 (2.3%) developed PE. Calibration was poor due to overestimation. Discrimination of 9 models for LO-PE ranged from 0.58 to 0.71 and of 9 models for all PE from 0.55 to 0.75. Conclusion: Only a few easily applicable prognostic models for all PE showed discrimination above 0.70, which is considered an acceptable performance.</p
Add to ORKG