Inflammasome-related genes expression in dengue patients, according to clinical classification.

The expression of (A) NLRP1, (B) NLRC4, (C) caspase-1, (D) IL-18 and (E) IL-1β in PBMCs was quantified by real time PCR by duplicated. The β-actin gene was used as a constitutive gene to normalize the mRNA content. The results are presented as medians with maximum and minimum values (box and whisker plot). Statistical comparison was made using the Kruskal-Wallis test with a confidence level of 95% and post hoc tests (or multiple benchmarks) HDS of Dunn, were applied. Significant differences are represented at the top of the figure (*p p p < 0.001).