The asymmetric allylation under the assistance of catalytic amounts of 3,3′-bis(2,4,6-triisopropylphenyl)-1,1′-binaphthyl-2,2′-diyl hydrogen phosphate (TRIP) allows the concise construction of the lignan scaffold from simple aldehydes and allylic bromides with full control of the two formed stereocenters. This young methodology has been employed to synthesize four naturally and pharmaceutically active lignans. Members of the dibenzylbutyrolactone, the tetraline, and the dibenzocyclooctadiene classes have been synthesized in 40–47% overall yield along four-step synthetic routes
Lignans are a wide spread class of natural compounds which mainly occur in plants as secondary plant...
1,2-Addition of 3,4-methylenedioxymagnesium bromide to 2-(R) and (S)-benzyloxy-2,5-dihydro-4-furanca...
Different strategies for the racemic or enantiospecific total syntheses of plant and mammalian 3,4-d...
The asymmetric allylation under the assistance of catalytic amounts of 3,3′-Bis(2,4,6-triisopropylph...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
Lignans are a structurally diverse class of natural products with extensive pharmacological effects....
This Ph. D. work is divided into two main projects. The first project is focused on the asymmetric s...
The asymmetric synthesis of the new lignan cubebin dimethyl ether was accomplished in eight steps wi...
Mimicking biosynthetic pathways of hongkonoids led to the development of a new Cu(Ⅰ)-catalyzed [3 + ...
Total syntheses of seven biologically important lignan natural products, including (-)-arctigenin, (...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
An asymmetric and regioselective total synthesis approach to 1,4-benzodioxane lignans was reported i...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
Finland has a long history of utilizing wood as fuel, construction material and for paper production...
Lignans are a wide spread class of natural compounds which mainly occur in plants as secondary plant...
1,2-Addition of 3,4-methylenedioxymagnesium bromide to 2-(R) and (S)-benzyloxy-2,5-dihydro-4-furanca...
Different strategies for the racemic or enantiospecific total syntheses of plant and mammalian 3,4-d...
The asymmetric allylation under the assistance of catalytic amounts of 3,3′-Bis(2,4,6-triisopropylph...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
A general and efficient method is described for the asymmetric synthesis of a variety of lignans. 5-...
Lignans are a structurally diverse class of natural products with extensive pharmacological effects....
This Ph. D. work is divided into two main projects. The first project is focused on the asymmetric s...
The asymmetric synthesis of the new lignan cubebin dimethyl ether was accomplished in eight steps wi...
Mimicking biosynthetic pathways of hongkonoids led to the development of a new Cu(Ⅰ)-catalyzed [3 + ...
Total syntheses of seven biologically important lignan natural products, including (-)-arctigenin, (...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
An asymmetric and regioselective total synthesis approach to 1,4-benzodioxane lignans was reported i...
Addition of dithianes, derived from alkyl- and aryl-aldehydes, to (5R)-menthyloxy-2[5H]-furanone fol...
Finland has a long history of utilizing wood as fuel, construction material and for paper production...
Lignans are a wide spread class of natural compounds which mainly occur in plants as secondary plant...
1,2-Addition of 3,4-methylenedioxymagnesium bromide to 2-(R) and (S)-benzyloxy-2,5-dihydro-4-furanca...
Different strategies for the racemic or enantiospecific total syntheses of plant and mammalian 3,4-d...