Additional file 11: of Expression of C-terminal ALK, RET, or ROS1 in lung cancer cells with or without fusion

Figure S7. Analysis by IHC and FISH of ALK in ILS31007 tissue specimen. The FFPE specimens with tumor tissue (upper panel) and the paired NAT specimens (lower panel) were obtained from BioreclamationIVT. IHC (left panel) and FISH (right panel) analyses for ALK rearrangement were performed with, respectively, the N-Histofine ALK detection kit (Nichirei Biosciences; Tokyo, Japan) and the Vysis ALK break apart FISH probe kit (Abbott laboratories; Abbott Park, IL) at a commercial clinical laboratory, LSI Medience (Tokyo, Japan). Images were captured using standard settings by the BZ900 (Keyence; Osaka, Japan) (PPTX 754 kb