Duplicate rate versus sequencing depth and target enrichment level in ER ChIP-seq data.

(A) Duplicate rate versus sequencing depth. (B) Enrichment level and the percentage of nonredundant reads in peaks. Duplicate rate was defined as the ratio of duplicate reads over uniquely mapped reads. Enrichment level was estimated as (number of nonredundant reads in peaks / total nonredundant reads in IP) / (number of nonredundant reads in peak-corresponding regions in input / total nonredundant reads in input).