Western diet effects on hepatic ω6-PUFA derived oxylipins.
- Manuel Garcia-Jaramillo (6551930)
- Melinda H. Spooner (6551933)
- Christiane V. Löhr (418937)
- Carmen P. Wong (512550)
- Weijian Zhang (446407)
- Donald B. Jump (498480)
Publication date
April 2019
DOI Publisher
Public Library of Science (PLoS)Abstract
ω6-PUFA derived oxylipins were quantified using a targeted LC/MS approach (Materials and methods). A: ω6 PUFA-derived oxylipins in RD-fed mice. B: Diet effects on ω6 PUFA-derived oxylipins. Results are presented as fold change in oxylipins induced by the WD. (mean ± SEM, N = 7–8 samples), *, FDR <0.05 versus the RD46 group. DiHOME, dihydroxyoctadecaenoic acid; HODE, hydroxyoctadecaenoic acid; PGE, prostaglandin E; PGF, prostaglandin F; HETE, hydroxyeicosatrienoic acid; DiHETrE, dihydroxyeicosatrienoic acid; LA, linoleic acid; ARA, arachidonic acid.</p
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