Figure S5. Remission as defined by CDAI (score ≤ 2.8) (a) and SDAI (score ≤ 3.3) (b) (observed). Baseline qualifying index study data were used for approximately 90% of patients. Italicized data not reported in figure due to low patient numbers. Data for 12-month intervals are reported in the tables. Database lock: March 2, 2017. BID twice daily, BL baseline, CDAI Clinical Disease Activity Index, SDAI Simplified Disease Activity Index, SE standard error
Rates reports of improvements meeting or exceeding clinically meaningful and normative values in bot...
Transition in CDAI for each group of patients administered TCZ at different intervals. Transition in...
Abstract Background Final data are presented for the ORAL Sequel long-term extension (LTE) study eva...
Figure S3. Mean (SE) ALT (a), AST (b), hemoglobin (c), and serum creatinine (d) over time. Baseline ...
Figure S2. All-cause AEs (a) and all-cause AEs leading to discontinuation (b) over time. Baseline qu...
Figure S1. Patient disposition (a) and discontinuation over time (b). aFour patients in the tofaciti...
Proportion and adjusted risk ratio of patients who achieved therapy effectiveness based on the modif...
Adjusted HR for time to serious infection in patients censored after they stopped/switched their ini...
Mean DAS parameters and DAS responder rates over time in the total population. (PDF 111 kb
Rates of reporting normative values for the Health Assessment Questionnaire-Disability Index (HAQ-DI...
Adjusted HR for time to serious infection in patients covered by Medicare (n = 5200). (DOCX 13 kb
ACR20 response rate and mean DAS28â4(ESR) and HAQ-DI over time for patients treated with tofacitin...
Mean change from baseline in ACR component parameters over time in the total population. (PDF 72 kb
Numbers needed to treat for ACR 20/50/70 (a), Disease Activity Score based on C reactive protein and...
Baseline and changes from baseline by visit prior to month 3 for patient-reported outcome measures; ...
Rates reports of improvements meeting or exceeding clinically meaningful and normative values in bot...
Transition in CDAI for each group of patients administered TCZ at different intervals. Transition in...
Abstract Background Final data are presented for the ORAL Sequel long-term extension (LTE) study eva...
Figure S3. Mean (SE) ALT (a), AST (b), hemoglobin (c), and serum creatinine (d) over time. Baseline ...
Figure S2. All-cause AEs (a) and all-cause AEs leading to discontinuation (b) over time. Baseline qu...
Figure S1. Patient disposition (a) and discontinuation over time (b). aFour patients in the tofaciti...
Proportion and adjusted risk ratio of patients who achieved therapy effectiveness based on the modif...
Adjusted HR for time to serious infection in patients censored after they stopped/switched their ini...
Mean DAS parameters and DAS responder rates over time in the total population. (PDF 111 kb
Rates of reporting normative values for the Health Assessment Questionnaire-Disability Index (HAQ-DI...
Adjusted HR for time to serious infection in patients covered by Medicare (n = 5200). (DOCX 13 kb
ACR20 response rate and mean DAS28â4(ESR) and HAQ-DI over time for patients treated with tofacitin...
Mean change from baseline in ACR component parameters over time in the total population. (PDF 72 kb
Numbers needed to treat for ACR 20/50/70 (a), Disease Activity Score based on C reactive protein and...
Baseline and changes from baseline by visit prior to month 3 for patient-reported outcome measures; ...
Rates reports of improvements meeting or exceeding clinically meaningful and normative values in bot...
Transition in CDAI for each group of patients administered TCZ at different intervals. Transition in...
Abstract Background Final data are presented for the ORAL Sequel long-term extension (LTE) study eva...