Figure S3. Examples of individual gene-pair MIij compared to respective simulated null distributions. Gene pairs in the top row are the five most highly significant interactions. Gene pairs in the bottom row are five randomly chosen non-significant pairs. Observed MI statistics are indicated with a red line and distributions based on a subsample of 10,000 simulations are plotted in grey
Eukaryotic genomes contain thousands of genes organized into complex and interconnected genetic inte...
<p>Networks of 91 pairs of genes showing significant evidence of interactions as identified by MFRG....
<p>The relative proportions (%) of intergenic distances between members of respective gene pairs are...
Figure S1. Histogram of observed MIij values (top) compared to a single randomly chosen simulation (...
Figure S4. False discovery rate was estimated by sampling nominally significant pairs in a subset of...
Figure S2. We measured observed and simulated MItot with a range of epsilon (ε) pseudocount values. ...
<p>Comparison of optimized-k Relief-F, standard Relief-F using k = 10 nearest neighbors, edgeR, and ...
Despite the emerging experimental techniques for perturbing multiple genes and measuring their quant...
The number of genetically interacting gene pairs from SGI, Lehner [24], the transposed SGA dataset [...
We investigate a variety of methods to first discover and then understand genetic interactions. Begi...
<p>Testing Accuracy for different combinations: single locus, 63.7 %; two locus, 65.1%; three locus,...
<p>(A) Mutual information values for any pairs of probe sets on Chr19. The middle point of each prob...
(A) Pairwise population comparison of heritability (h2) and rG for each gene. The y-axis is the mini...
Eukaryotic genomes contain thousands of genes organized into complex and interconnected genetic inte...
Eukaryotic genomes contain thousands of genes organized into complex and interconnected genetic inte...
Eukaryotic genomes contain thousands of genes organized into complex and interconnected genetic inte...
<p>Networks of 91 pairs of genes showing significant evidence of interactions as identified by MFRG....
<p>The relative proportions (%) of intergenic distances between members of respective gene pairs are...
Figure S1. Histogram of observed MIij values (top) compared to a single randomly chosen simulation (...
Figure S4. False discovery rate was estimated by sampling nominally significant pairs in a subset of...
Figure S2. We measured observed and simulated MItot with a range of epsilon (ε) pseudocount values. ...
<p>Comparison of optimized-k Relief-F, standard Relief-F using k = 10 nearest neighbors, edgeR, and ...
Despite the emerging experimental techniques for perturbing multiple genes and measuring their quant...
The number of genetically interacting gene pairs from SGI, Lehner [24], the transposed SGA dataset [...
We investigate a variety of methods to first discover and then understand genetic interactions. Begi...
<p>Testing Accuracy for different combinations: single locus, 63.7 %; two locus, 65.1%; three locus,...
<p>(A) Mutual information values for any pairs of probe sets on Chr19. The middle point of each prob...
(A) Pairwise population comparison of heritability (h2) and rG for each gene. The y-axis is the mini...
Eukaryotic genomes contain thousands of genes organized into complex and interconnected genetic inte...
Eukaryotic genomes contain thousands of genes organized into complex and interconnected genetic inte...
Eukaryotic genomes contain thousands of genes organized into complex and interconnected genetic inte...
<p>Networks of 91 pairs of genes showing significant evidence of interactions as identified by MFRG....
<p>The relative proportions (%) of intergenic distances between members of respective gene pairs are...