Representative MHC gels (A, B) for soleus and EDL muscles, loaded with a pooled sample (Mixed) used to generate the Calibration curve (see Methods), with (C, D) showing percentage of different MHC in soleus and EDL muscles. ** BLAJ significantly different to WT (ps < 0.01). Data are presented as individual values with horizontal lines indicating mean ± SD.</p
<p>(A) Hindlimb from transgenic mice of the 86 line compared to wild-type animals at 2 months of age...
<p>Skeletal muscle (<i>gastrocnemius</i>) was harvested from CHC22-mice and WT mice at the indicated...
<p>A: body weight of male (empty diamonds) and female (empty triangles) wild-type mice, and male (fi...
<p>At 29 months, there was no significant loss of myofibres in the EDL (A), but a significant loss i...
<p>(A) Representative gels stained with coomassie blue showing the myosin heavy chain (MyHC) protein...
<p>Muscle fiber composition for EDL was assessed on a single fiber basis. For this MyHC were extract...
<p>A) Cross-sections of soleus, EDL, and interscutularis muscles from young adult mice stained with ...
<p>There are no error bars on some of the graphs (D,F) as the myofibre types were present in less th...
Graphs displaying the average longitudinal values of the mdx4cv and control mice muscles in the T2, ...
<p>A) MyHC isoforms were separated by SDS-PAGE and stained with Coomassie blue. Densitometric analys...
<p>H&E staining of EDL muscle sections from WT, mdx/utrn +/+, and mdx/utrn +/- mice at 1, 2, and 5 m...
<p>Number (a and b) and diameter (c,d and e) of the muscle fibers after 2 months of ML. Of note, sin...
<p>A) Representative gel image of tissue homogenates from bladder, aortic and ileal tissues from <i>...
<p>Tibialis anterior muscles were snap-frozen, sliced transversally and immunostained. BGT-AF647 (A–...
<p>(A) Low and high magnification images of Ctl and IH diaphragm sections immunostained for type I m...
<p>(A) Hindlimb from transgenic mice of the 86 line compared to wild-type animals at 2 months of age...
<p>Skeletal muscle (<i>gastrocnemius</i>) was harvested from CHC22-mice and WT mice at the indicated...
<p>A: body weight of male (empty diamonds) and female (empty triangles) wild-type mice, and male (fi...
<p>At 29 months, there was no significant loss of myofibres in the EDL (A), but a significant loss i...
<p>(A) Representative gels stained with coomassie blue showing the myosin heavy chain (MyHC) protein...
<p>Muscle fiber composition for EDL was assessed on a single fiber basis. For this MyHC were extract...
<p>A) Cross-sections of soleus, EDL, and interscutularis muscles from young adult mice stained with ...
<p>There are no error bars on some of the graphs (D,F) as the myofibre types were present in less th...
Graphs displaying the average longitudinal values of the mdx4cv and control mice muscles in the T2, ...
<p>A) MyHC isoforms were separated by SDS-PAGE and stained with Coomassie blue. Densitometric analys...
<p>H&E staining of EDL muscle sections from WT, mdx/utrn +/+, and mdx/utrn +/- mice at 1, 2, and 5 m...
<p>Number (a and b) and diameter (c,d and e) of the muscle fibers after 2 months of ML. Of note, sin...
<p>A) Representative gel image of tissue homogenates from bladder, aortic and ileal tissues from <i>...
<p>Tibialis anterior muscles were snap-frozen, sliced transversally and immunostained. BGT-AF647 (A–...
<p>(A) Low and high magnification images of Ctl and IH diaphragm sections immunostained for type I m...
<p>(A) Hindlimb from transgenic mice of the 86 line compared to wild-type animals at 2 months of age...
<p>Skeletal muscle (<i>gastrocnemius</i>) was harvested from CHC22-mice and WT mice at the indicated...
<p>A: body weight of male (empty diamonds) and female (empty triangles) wild-type mice, and male (fi...