Ghrelin is an important orexigenic hormone that regulates feeding, metabolism and glucose homeostasis in human and rodents. Ghrelin functions by binding to its receptor, the growth hormone secretagogue receptor 1a (GHS-R1a), which is widely expressed inside and outside of the brain. Recent studies suggested that acyl-ghrelin, the active form of ghrelin, is a persistent biomarker for chronic stress exposure. However, how ghrelin/GHS-R1a signaling contributes to stress responses and mood regulation remains uncertain. In this study, we applied the chronic social defeat stress (CSDS) paradigm to both GHS-R1a knock-out (Ghsr-/-) mice and littermate control (Ghsr+/+) mice, and then measured their depression- and anxiety-related behaviors. We foun...
This study aims to examine the antidepressant-like action of Ghrelin (Ghr), a hormone synthesized pr...
The orexigenic hormone ghrelin is being increasingly recognized as a stress hormone being involved i...
Depression and anxiety disorders are often characterized by altered hypothalamic-pituitary-adrenal (...
Ghrelin is an important orexigenic hormone that regulates feeding, metabolism and glucose homeostasi...
Ghrelin is an important orexigenic hormone that regulates feeding, metabolism and glucose homeostasi...
Ghrelin plays important roles in glucose metabolism, appetite, and body weight regulation, and recen...
The ghrelin receptor is now known to play an important role in regulating physiological responses to...
Contains fulltext : 155371.pdf (publisher's version ) (Closed access)Ghrelin is a ...
Ghrelin (Ghr) is an orexigenic peptide that is being investigated for its potential role in developm...
BACKGROUND: Obesity is a risk factor for stress-related mental disorders such as post-traumatic stre...
Chronic stressors promote metabolic disturbances, including obesity and metabolic syndrome. Ghrelin,...
The amygdala complex is strongly involved in the formation of emotional memories, and GHS-R1a was fo...
Chronic social stress has been associated with increased caloric intake and adiposity. These effects...
AbstractThe central ghrelin signaling system engages key pathways of importance for feeding control,...
Hormones in the hypothalamus–pituitary–adrenal (HPA) axis mediate many of the bodily responses to st...
This study aims to examine the antidepressant-like action of Ghrelin (Ghr), a hormone synthesized pr...
The orexigenic hormone ghrelin is being increasingly recognized as a stress hormone being involved i...
Depression and anxiety disorders are often characterized by altered hypothalamic-pituitary-adrenal (...
Ghrelin is an important orexigenic hormone that regulates feeding, metabolism and glucose homeostasi...
Ghrelin is an important orexigenic hormone that regulates feeding, metabolism and glucose homeostasi...
Ghrelin plays important roles in glucose metabolism, appetite, and body weight regulation, and recen...
The ghrelin receptor is now known to play an important role in regulating physiological responses to...
Contains fulltext : 155371.pdf (publisher's version ) (Closed access)Ghrelin is a ...
Ghrelin (Ghr) is an orexigenic peptide that is being investigated for its potential role in developm...
BACKGROUND: Obesity is a risk factor for stress-related mental disorders such as post-traumatic stre...
Chronic stressors promote metabolic disturbances, including obesity and metabolic syndrome. Ghrelin,...
The amygdala complex is strongly involved in the formation of emotional memories, and GHS-R1a was fo...
Chronic social stress has been associated with increased caloric intake and adiposity. These effects...
AbstractThe central ghrelin signaling system engages key pathways of importance for feeding control,...
Hormones in the hypothalamus–pituitary–adrenal (HPA) axis mediate many of the bodily responses to st...
This study aims to examine the antidepressant-like action of Ghrelin (Ghr), a hormone synthesized pr...
The orexigenic hormone ghrelin is being increasingly recognized as a stress hormone being involved i...
Depression and anxiety disorders are often characterized by altered hypothalamic-pituitary-adrenal (...