Bacteriostatic and bactericidal efficacy of 10-undecynoic acid on planktonic form of <i>Streptococcus mutans</i> UA159 and <i>Streptococcus sobrinus</i> SL1.

(A) Time-dependent effect of different concentrations of 10-undecynoic acid assessed by plating method up to 24 h. (B) Time-dependent effect of MIC and MBC values of 10-undecynoic acid assessed by macro-dilution method up to 24 h. MBC values were determined from broth macro-dilution minimum inhibitory concentration test by sub-culturing it to BHI agar plates that do not contain the test agent. Control– 0.1% DMSO, 10-UDYA– 10-undecynoic acid, # p<0.05, * p<0.001 compared to control.