Correlation analysis between the frequency of circulating mMDSCs and clinical parameters.

The correlation between mMDSCs percentage in monocytes and the levels of HBsAg (A) or HBV DNA (B) from HBeAg (+) patients (red) and HBeAg (-) patients (blue) were analyzed by Spearman correlation. (C) Correlation analysis between the frequency of mMDSCs and HBeAg level in HBeAg (+) patients. (D) Unsupervised hierarchical clustering using Euclidean distance; dendrogram displaying similarity between clusters. Clinically assigned disease phase shown adjacent to plot (not used for analysis). Increasing color intensity (blue→ red) corresponds to increasing mMDSC frequency, serum HBsAg (IU/ml), HBeAg (S/CO), or ALT (U/l).