COG categories of Tn-Seq candidate fitness factors.

The percentage of candidate P. mirabilis fitness factors required for growth in RPMI, 50% heat-inactivated naive mouse serum and 50% heat-inactivated acute phase mouse serum belonging to each Cluster of Orthologous Groups of proteins (COG). The percentage of candidate infection-specific P. mirabilis fitness factors during colonization of the murine spleen and liver 24 hours post-inoculation belonging to each COG, for which only genes identified during infection that had no defect in vitro are represented. The total number of fitness factors for each group with an identified COG category is listed under its respective pie chart.