Sera collected before and after DENV challenge were tested for their concentration in the indicated immune mediators. (A) Shown are the mean changes from baseline and SEM (n = 5 but Gr.3/DENV-2 S16803, n = 4). The log10-transformed changes from baseline were analyzed using an ANCOVA model. The p-values compare vaccinated to their corresponding non-vaccinated control subgroups with color codes referring to the vaccinated groups (*, pppppp<0.001).</p
<p>The three vaccinated macaques that did not show any evidence of infection had high titer of anti-...
<p>Virus infection status was determined by PCR for SIV<i>gag</i> proviral DNA and virus isolation (...
<p>Anti-Env IgG antibody titers were determined in plasma of control (<b>A</b>) and vaccinated (<b>B...
<p>(A) List of vaccinees with or without passive immunization. (B) Plasma viral loads after challeng...
Three groups of rhesus macaques received two intra-muscular administrations, 28 days apart, of the i...
<p>Five of the 38 macaques showed increases in anti-Tn IgG (A) and/or IgM (B). For these 5 animals, ...
<p>Antibodies reactive against (A) the ecto-domain of the WNV E protein, and (B) inactivated WNV wer...
<p>(A) List of naive controls and NAb-immunized macaques. Experiments using macaques indicated by as...
<p>Intracellular levels of TNF-α were determined in CD4- and CD8-positive T-cell populations before ...
Using whole-blood transcriptional profiling, we investigated differences in the host response to vac...
<p>(<b>A</b>) Percentage of MDDCs internalizing Env in the presence of plasma from Tat/Env vaccinate...
<p>(A) Changes in plasma viral loads after challenge vaccinated macaques possessing MHC-I haplotype ...
<p>Post-infection changes in anti-glycan antibody levels were repeated for overall week 64 (22 weeks...
<p>Macaques were challenged with an intravenous dose of SIV<sub>mac</sub>251<sub>NE</sub> on week 46...
<p>Sera were collected in the indicated weeks after the first vaccination. Sera of week 2 were obtai...
<p>The three vaccinated macaques that did not show any evidence of infection had high titer of anti-...
<p>Virus infection status was determined by PCR for SIV<i>gag</i> proviral DNA and virus isolation (...
<p>Anti-Env IgG antibody titers were determined in plasma of control (<b>A</b>) and vaccinated (<b>B...
<p>(A) List of vaccinees with or without passive immunization. (B) Plasma viral loads after challeng...
Three groups of rhesus macaques received two intra-muscular administrations, 28 days apart, of the i...
<p>Five of the 38 macaques showed increases in anti-Tn IgG (A) and/or IgM (B). For these 5 animals, ...
<p>Antibodies reactive against (A) the ecto-domain of the WNV E protein, and (B) inactivated WNV wer...
<p>(A) List of naive controls and NAb-immunized macaques. Experiments using macaques indicated by as...
<p>Intracellular levels of TNF-α were determined in CD4- and CD8-positive T-cell populations before ...
Using whole-blood transcriptional profiling, we investigated differences in the host response to vac...
<p>(<b>A</b>) Percentage of MDDCs internalizing Env in the presence of plasma from Tat/Env vaccinate...
<p>(A) Changes in plasma viral loads after challenge vaccinated macaques possessing MHC-I haplotype ...
<p>Post-infection changes in anti-glycan antibody levels were repeated for overall week 64 (22 weeks...
<p>Macaques were challenged with an intravenous dose of SIV<sub>mac</sub>251<sub>NE</sub> on week 46...
<p>Sera were collected in the indicated weeks after the first vaccination. Sera of week 2 were obtai...
<p>The three vaccinated macaques that did not show any evidence of infection had high titer of anti-...
<p>Virus infection status was determined by PCR for SIV<i>gag</i> proviral DNA and virus isolation (...
<p>Anti-Env IgG antibody titers were determined in plasma of control (<b>A</b>) and vaccinated (<b>B...