Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice - Fig 3

Muscle susceptibility to lengthening contractions (fragility) in the first series of experiments (A) and utrophin expression (B) in treated mdx mice. Sed: non-treated sedentary mdx mice; Run: exercised and treated with vehicle; Run+CLi-Low: exercised and treated mdx mice with 20 μg/kg CLi; Run+CLi-High: exercised and treated mdx mice with 100 μg/kg CLi. n = 14–18 per group for A; n = 7–9 per group for figure B. b: significantly different from Run mice (p<0.05).