Abstract Objective To evaluate the rs42524 polymorphism of the procollagen type I alpha (α) 2 (COL1A2) gene as a factor related to the development of pelvic organ prolapse (POP) in Brazilian women. Methods The present study involved 112 women with POP stages III and IV (case group) and 180 women with POP stages zero and I (control group). Other clinical data were obtained by interviewing the patients about their medical history, and blood was also collected from the volunteers for the extraction of genomic DNA. The promoter region of the COL1A2 gene containing the rs42524 polymorphism was amplified, and the discrimination between the G and C variants was performed by digestion of the polymerase chain reaction (PCR) products with the Msp...
OBJECTIVE: Apoptotic cell death, probably induced by oxidative stress, contributes to the developmen...
PURPOSE: To evaluate the possible influence of G-->T substitution at the Sp1-binding site of the COL...
PURPOSE: We investigated the role of COL3A1 exon 31 polymorphism (a single base substitution from gu...
The objective of this study was to verify the possible association between the Sp1-binding site poly...
[[abstract]]Objective To investigate whether pelvic organ prolapse (POP) is associated with collagen...
This paper describes the relationship of polymorphisms of the collagen genes COL1A1 and COL3A1 and p...
INTRODUCTION AND HYPOTHESIS: A familial tendency has been demonstrated in the etiology of pelvic org...
Objective: Verify the association between genital prolapse, other risk factors and a polymorphism in...
INTRODUCTION AND HYPOTHESIS: A familial tendency has been demonstrated in the etiology of pelvic org...
INTRODUCTION AND HYPOTHESIS: A familial tendency has been demonstrated in the etiology of pelvic org...
Objective: To verify the possible association between the presence of the polymorphism in exon 31 of...
Introduction and hypothesis We verified the presence of single nucleotide polymorphisms (SNP) rs2236...
INTRODUCTION AND HYPOTHESIS: The rs1800255, COL3A1 2209 G>A polymorphism in the alpha 1 chain of col...
INTRODUCTION AND HYPOTHESIS: The rs1800255, COL3A1 2209 G>A polymorphism in the alpha 1 chain of ...
학위논문 (석사)-- 서울대학교 대학원 : 임상의과학과, 2013. 2. 전명재.Introduction: Apoptotic cell death, likely induced by o...
OBJECTIVE: Apoptotic cell death, probably induced by oxidative stress, contributes to the developmen...
PURPOSE: To evaluate the possible influence of G-->T substitution at the Sp1-binding site of the COL...
PURPOSE: We investigated the role of COL3A1 exon 31 polymorphism (a single base substitution from gu...
The objective of this study was to verify the possible association between the Sp1-binding site poly...
[[abstract]]Objective To investigate whether pelvic organ prolapse (POP) is associated with collagen...
This paper describes the relationship of polymorphisms of the collagen genes COL1A1 and COL3A1 and p...
INTRODUCTION AND HYPOTHESIS: A familial tendency has been demonstrated in the etiology of pelvic org...
Objective: Verify the association between genital prolapse, other risk factors and a polymorphism in...
INTRODUCTION AND HYPOTHESIS: A familial tendency has been demonstrated in the etiology of pelvic org...
INTRODUCTION AND HYPOTHESIS: A familial tendency has been demonstrated in the etiology of pelvic org...
Objective: To verify the possible association between the presence of the polymorphism in exon 31 of...
Introduction and hypothesis We verified the presence of single nucleotide polymorphisms (SNP) rs2236...
INTRODUCTION AND HYPOTHESIS: The rs1800255, COL3A1 2209 G>A polymorphism in the alpha 1 chain of col...
INTRODUCTION AND HYPOTHESIS: The rs1800255, COL3A1 2209 G>A polymorphism in the alpha 1 chain of ...
학위논문 (석사)-- 서울대학교 대학원 : 임상의과학과, 2013. 2. 전명재.Introduction: Apoptotic cell death, likely induced by o...
OBJECTIVE: Apoptotic cell death, probably induced by oxidative stress, contributes to the developmen...
PURPOSE: To evaluate the possible influence of G-->T substitution at the Sp1-binding site of the COL...
PURPOSE: We investigated the role of COL3A1 exon 31 polymorphism (a single base substitution from gu...