Additional file 4: of SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Morvarid Saeinasab (6627422)
Ahmad Bahrami (6627425)
Jovanna GonzĂĄlez (4541758)
Francesco Marchese (6627431)
Dannys Martinez (4541752)
Seyed Mowla (5722292)
Maryam Matin (6627434)
Maite Huarte (4541767)

Publication date

April 2019

DOI

10.6084/m9.figshare.8032895.v1

Abstract

Figure S1. Association possibility of SNHG15 to polysomes, GAPDH expression was evaluated as a positive control. (PNG 1830 kb

Extracted data

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Data Protection

Additional file 4: of SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Morvarid Saeinasab (6627422)
Ahmad Bahrami (6627425)
Jovanna GonzĂĄlez (4541758)
Francesco Marchese (6627431)
Dannys Martinez (4541752)
Seyed Mowla (5722292)
Maryam Matin (6627434)
Maite Huarte (4541767)

Open link

Publication date

April 2019

DOI

10.6084/m9.figshare.8032895.v1

Abstract

Figure S1. Association possibility of SNHG15 to polysomes, GAPDH expression was evaluated as a positive control. (PNG 1830 kb

Extracted data

Han Li (10885)
Yixue Xue (133703)
Jun Ma (9393)
Lianqi Shao (6309878)
Di Wang (329735)
Jian Zheng (287758)
Xiaobai Liu (3760144)
Chunqing Yang (6271727)
Qianru He (2078950)
Xuelei Ruan (5845916)
Zhen Li (49109)
Yunhui Liu (133710)

February 2019

Figure S1. SNHG1 also bound to pre-miR-376b-3p with A to I edited. Schematic representation of the p...

Additional file 4: of The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

Eleanor O’Brien (4873927)
Joanna Selfe (4873918)
Ana Martins (187412)
Zoë Walters (4873924)
Janet Shipley (84426)

February 2018

Figure S4. Effect of MYCNOS-01 overexpression on MYCN transcript and protein expression. qRT-PCR det...

Additional file 3: of Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer

Kuo-Wang Tsai (3459218)
Yi-Hao Lo (4928116)
Hsuan Liu (589528)
Chung-Yu Yeh (4928113)
You-Zuo Chen (4928122)
Chao-Wen Hsu (4928125)
Wei-Shone Chen (761273)
Jui-Ho Wang (4928119)

March 2018

Figure S3. Examination of the subcellular fractionation localization of Linc00659 in CRC cell lines....

Additional file 3: of SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Morvarid Saeinasab (6627422)
Ahmad Bahrami (6627425)
Jovanna GonzĂĄlez (4541758)
Francesco Marchese (6627431)
Dannys Martinez (4541752)
Seyed Mowla (5722292)
Maryam Matin (6627434)
Maite Huarte (4541767)

April 2019

Table S3. The most significantly deregulated lncRNAs with high expression correlated with low surviv...

Additional file 5: of SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Morvarid Saeinasab (6627422)
Ahmad Bahrami (6627425)
Jovanna González (6627458)
Francesco Marchese (6627431)
Dannys Martinez (4541752)
Seyed Mowla (5722292)
Maryam Matin (6627434)
Maite Huarte (4541767)

April 2019

Figure S2. (A) Cell cycle analysis of CRC cells after synchronization with double thymidine block pr...

SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Saeinasab, M. (Morvarid)
Bahrami, A.R. (Ahmad Reza)
Gonzalez-Rojas, S.J. (Sandra Jovanna)
Marchese, F.P. (Francesco P.)
Martínez, D. (Dannys)
Mowla, S.J. (Seyed Javad)
Matin, M.M. (Maryam M.)
Huarte, M. (Maite)

January 2019

Background: Thousands of long noncoding RNAs (lncRNAs) are aberrantly expressed in various types of ...

Additional file 5: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S1. SNHG1 is up-regulated in cancers, related to Fig. 1. (a) The SNHG1 expression in differen...

Additional file 6: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S2. SP1 is up-regulated in colorectal cancer and positively correlated with SNHG1, related to...

Additional file 9: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S5. SNHG1 is involved in epigenetic repression of KLF2 and P15 by interacting with PRC2., rel...

Additional file 10: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S6. SNHG1 promotes HCT-8 cell growth partly by regulating KLF2 and CDKN2B expression., relate...

Additional file 8: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S4. SNHG1 regulates CCND2 expression by competitively binding miR-154-5p, related to Fig. 6. ...

Additional file 7: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S3. SNHG1 acts as a ceRNA for miR-154-5p, related to Fig. 5. (a) RNA immunoprecipitation with...

Additional file 1: of Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression

Yang Li (7082)
Changqian Zeng (5480291)
Jialei Hu (3938267)
Yue Pan (267516)
Yujia Shan (5480294)
Bing Liu (70818)
Li Jia (76051)

July 2018

Figure S1. PI3K/Akt/mTOR pathway inhibition modulates the proliferation and invasion of SW620 cells....

Additional file 14: of Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development

Patrizia Sarogni (6417833)
Orazio Palumbo (174177)
Adele Servadio (6417836)
Simonetta Astigiano (277590)
Barbara D’Alessio (6417860)
Veronica Gatti (6417842)
Dubravka Cukrov (6417845)
Silvia Baldari (6417848)
Maria Pallotta (6417851)
Paolo Aretini (3577613)
Felice Dell’Orletta (6417863)
Silvia Soddu (261300)
Massimo Carella (174251)
Gabriele Toietta (6417857)
Ottavia Barbieri (273401)
Gabriella Fontanini (3563849)
Antonio Musio (760453)

March 2019

Figure S15. Dysregulated genes in induced tumors. RNA-seq data was validated for eleven genes, ATG12...

Additional file 4: of N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway

Yu Yin (329063)
Lingfan Xu (767722)
Yan Chang (486484)
Tao Zeng (103451)
Xufeng Chen (499602)
Aifeng Wang (6245345)
Jeff Groth (6245348)
Wen-Chi Foo (6245351)
Chaozhao Liang (212565)
Hailiang Hu (413269)
Jiaoti Huang (88989)

January 2019

Figure S4. N-Myc overexpression in LNCaP and 22RV1 cells differentially regulates the expression of ...

Additional file 1: of SNHG1 promotes malignant biological behaviors of glioma cells via microRNA-154-5p/miR-376b-3p- FOXP2- KDM5B participating positive feedback loop

Han Li (10885)
Yixue Xue (133703)
Jun Ma (9393)
Lianqi Shao (6309878)
Di Wang (329735)
Jian Zheng (287758)
Xiaobai Liu (3760144)
Chunqing Yang (6271727)
Qianru He (2078950)
Xuelei Ruan (5845916)
Zhen Li (49109)
Yunhui Liu (133710)

February 2019

Figure S1. SNHG1 also bound to pre-miR-376b-3p with A to I edited. Schematic representation of the p...

Additional file 4: of The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

Eleanor O’Brien (4873927)
Joanna Selfe (4873918)
Ana Martins (187412)
Zoë Walters (4873924)
Janet Shipley (84426)

February 2018

Figure S4. Effect of MYCNOS-01 overexpression on MYCN transcript and protein expression. qRT-PCR det...

Additional file 3: of Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer

Kuo-Wang Tsai (3459218)
Yi-Hao Lo (4928116)
Hsuan Liu (589528)
Chung-Yu Yeh (4928113)
You-Zuo Chen (4928122)
Chao-Wen Hsu (4928125)
Wei-Shone Chen (761273)
Jui-Ho Wang (4928119)

March 2018

Figure S3. Examination of the subcellular fractionation localization of Linc00659 in CRC cell lines....

Morvarid Saeinasab (6627422)
Ahmad Bahrami (6627425)
Jovanna GonzĂĄlez (4541758)
Francesco Marchese (6627431)
Dannys Martinez (4541752)
Seyed Mowla (5722292)
Maryam Matin (6627434)
Maite Huarte (4541767)

April 2019

Table S3. The most significantly deregulated lncRNAs with high expression correlated with low surviv...

Morvarid Saeinasab (6627422)
Ahmad Bahrami (6627425)
Jovanna González (6627458)
Francesco Marchese (6627431)
Dannys Martinez (4541752)
Seyed Mowla (5722292)
Maryam Matin (6627434)
Maite Huarte (4541767)

April 2019

Figure S2. (A) Cell cycle analysis of CRC cells after synchronization with double thymidine block pr...

SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Saeinasab, M. (Morvarid)
Bahrami, A.R. (Ahmad Reza)
Gonzalez-Rojas, S.J. (Sandra Jovanna)
Marchese, F.P. (Francesco P.)
Martínez, D. (Dannys)
Mowla, S.J. (Seyed Javad)
Matin, M.M. (Maryam M.)
Huarte, M. (Maite)

January 2019

Background: Thousands of long noncoding RNAs (lncRNAs) are aberrantly expressed in various types of ...

Additional file 5: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S1. SNHG1 is up-regulated in cancers, related to Fig. 1. (a) The SNHG1 expression in differen...

Additional file 6: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S2. SP1 is up-regulated in colorectal cancer and positively correlated with SNHG1, related to...

Additional file 9: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S5. SNHG1 is involved in epigenetic repression of KLF2 and P15 by interacting with PRC2., rel...

Additional file 10: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S6. SNHG1 promotes HCT-8 cell growth partly by regulating KLF2 and CDKN2B expression., relate...

Additional file 8: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S4. SNHG1 regulates CCND2 expression by competitively binding miR-154-5p, related to Fig. 6. ...

Additional file 7: of The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

Mu Xu (594466)
Xiaoxiang Chen (730749)
Kang Lin (5530313)
Kaixuan Zeng (5802707)
Xiangxiang Liu (617225)
Bei Pan (5560136)
Xueni Xu (5802710)
Tao Xu (3537)
Xiuxiu Hu (5802713)
Li Sun (4624)
Bangshun He (119526)
Yuqin Pan (119528)
Huiling Sun (530956)
Shukui Wang (119550)

September 2018

Figure S3. SNHG1 acts as a ceRNA for miR-154-5p, related to Fig. 5. (a) RNA immunoprecipitation with...

Additional file 1: of Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression

Yang Li (7082)
Changqian Zeng (5480291)
Jialei Hu (3938267)
Yue Pan (267516)
Yujia Shan (5480294)
Bing Liu (70818)
Li Jia (76051)

July 2018

Figure S1. PI3K/Akt/mTOR pathway inhibition modulates the proliferation and invasion of SW620 cells....

Additional file 14: of Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development

Patrizia Sarogni (6417833)
Orazio Palumbo (174177)
Adele Servadio (6417836)
Simonetta Astigiano (277590)
Barbara D’Alessio (6417860)
Veronica Gatti (6417842)
Dubravka Cukrov (6417845)
Silvia Baldari (6417848)
Maria Pallotta (6417851)
Paolo Aretini (3577613)
Felice Dell’Orletta (6417863)
Silvia Soddu (261300)
Massimo Carella (174251)
Gabriele Toietta (6417857)
Ottavia Barbieri (273401)
Gabriella Fontanini (3563849)
Antonio Musio (760453)

March 2019

Figure S15. Dysregulated genes in induced tumors. RNA-seq data was validated for eleven genes, ATG12...

Additional file 4: of N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway

Yu Yin (329063)
Lingfan Xu (767722)
Yan Chang (486484)
Tao Zeng (103451)
Xufeng Chen (499602)
Aifeng Wang (6245345)
Jeff Groth (6245348)
Wen-Chi Foo (6245351)
Chaozhao Liang (212565)
Hailiang Hu (413269)
Jiaoti Huang (88989)

January 2019

Figure S4. N-Myc overexpression in LNCaP and 22RV1 cells differentially regulates the expression of ...

Additional file 1: of SNHG1 promotes malignant biological behaviors of glioma cells via microRNA-154-5p/miR-376b-3p- FOXP2- KDM5B participating positive feedback loop

Han Li (10885)
Yixue Xue (133703)
Jun Ma (9393)
Lianqi Shao (6309878)
Di Wang (329735)
Jian Zheng (287758)
Xiaobai Liu (3760144)
Chunqing Yang (6271727)
Qianru He (2078950)
Xuelei Ruan (5845916)
Zhen Li (49109)
Yunhui Liu (133710)

February 2019

Figure S1. SNHG1 also bound to pre-miR-376b-3p with A to I edited. Schematic representation of the p...

Additional file 4: of The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

Eleanor O’Brien (4873927)
Joanna Selfe (4873918)
Ana Martins (187412)
Zoë Walters (4873924)
Janet Shipley (84426)

February 2018

Figure S4. Effect of MYCNOS-01 overexpression on MYCN transcript and protein expression. qRT-PCR det...

Additional file 3: of Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer

Kuo-Wang Tsai (3459218)
Yi-Hao Lo (4928116)
Hsuan Liu (589528)
Chung-Yu Yeh (4928113)
You-Zuo Chen (4928122)
Chao-Wen Hsu (4928125)
Wei-Shone Chen (761273)
Jui-Ho Wang (4928119)

March 2018

Figure S3. Examination of the subcellular fractionation localization of Linc00659 in CRC cell lines....

Additional file 4: of SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Abstract

Extracted data

Additional file 4: of SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

Abstract

Extracted data

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